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Determination of absolute configuration and binding efficacy of benzimidazole-based FabI inhibitors through the support of electronic circular dichroism and MM-GBSA techniques.
Ren J, Mistry TL, Su PC, Mehboob S, Demissie R, Fung LW, Ghosh AK, Johnson ME. Ren J, et al. Among authors: johnson me. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2074-2079. doi: 10.1016/j.bmcl.2018.04.052. Epub 2018 Apr 22. Bioorg Med Chem Lett. 2018. PMID: 29730028 Free PMC article.
Hit-to-Lead: Hit Validation and Assessment.
Hevener KE, Pesavento R, Ren J, Lee H, Ratia K, Johnson ME. Hevener KE, et al. Among authors: johnson me. Methods Enzymol. 2018;610:265-309. doi: 10.1016/bs.mie.2018.09.022. Epub 2018 Oct 25. Methods Enzymol. 2018. PMID: 30390802
Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of vraTSR Expression in Methicillin-Resistant Staphylococcus aureus.
Lee H, Boyle-Vavra S, Ren J, Jarusiewicz JA, Sharma LK, Hoagland DT, Yin S, Zhu T, Hevener KE, Ojeda I, Lee RE, Daum RS, Johnson ME. Lee H, et al. Among authors: johnson me. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e02593-18. doi: 10.1128/AAC.02593-18. Print 2019 Sep. Antimicrob Agents Chemother. 2019. PMID: 31209003 Free PMC article.
754 results