Tong L - Search Results

1

Multivalent Small-Molecule Pan-RAS Inhibitors.

Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR. Welsch ME, et al. Among authors: tong l. Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006. Cell. 2017. PMID: 28235199 Free PMC article.

2

Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase.

Huang CS, Sadre-Bazzaz K, Shen Y, Deng B, Zhou ZH, Tong L. Huang CS, et al. Among authors: tong l. Nature. 2010 Aug 19;466(7309):1001-5. doi: 10.1038/nature09302. Nature. 2010. PMID: 20725044 Free PMC article.

3

An unanticipated architecture of the 750-kDa α6β6 holoenzyme of 3-methylcrotonyl-CoA carboxylase.

Huang CS, Ge P, Zhou ZH, Tong L. Huang CS, et al. Among authors: tong l. Nature. 2011 Dec 11;481(7380):219-23. doi: 10.1038/nature10691. Nature. 2011. PMID: 22158123 Free PMC article.

4

Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase.

Tran TH, Hsiao YS, Jo J, Chou CY, Dietrich LE, Walz T, Tong L. Tran TH, et al. Among authors: tong l. Nature. 2015 Feb 5;518(7537):120-4. doi: 10.1038/nature13912. Epub 2014 Nov 10. Nature. 2015. PMID: 25383525 Free PMC article.

5

Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase.

Jurado AR, Huang CS, Zhang X, Zhou ZH, Tong L. Jurado AR, et al. Among authors: tong l. Nat Commun. 2015 Nov 23;6:8986. doi: 10.1038/ncomms9986. Nat Commun. 2015. PMID: 26593090 Free PMC article.

6

Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer.

Maderbocus R, Fields BL, Hamilton K, Luo S, Tran TH, Dietrich LEP, Tong L. Maderbocus R, et al. Among authors: tong l. Nat Commun. 2017 Jul 31;8(1):160. doi: 10.1038/s41467-017-00233-z. Nat Commun. 2017. PMID: 28757619 Free PMC article.

7

NMR Signal Quenching from Bound Biradical Affinity Reagents in DNP Samples.

Rogawski R, Sergeyev IV, Zhang Y, Tran TH, Li Y, Tong L, McDermott AE. Rogawski R, et al. Among authors: tong l. J Phys Chem B. 2017 Dec 7;121(48):10770-10781. doi: 10.1021/acs.jpcb.7b08274. Epub 2017 Nov 29. J Phys Chem B. 2017. PMID: 29116793 Free PMC article.

8

Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore.

Taylor SK, Tran TH, Liu MZ, Harris PE, Sun Y, Jambawalikar SR, Tong L, Stojanovic MN. Taylor SK, et al. Among authors: tong l. Chemistry. 2018 Jul 25;24(42):10646-10652. doi: 10.1002/chem.201801388. Epub 2018 Jul 4. Chemistry. 2018. PMID: 29873848 Free PMC article.

9

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.

Dieck CL, Tzoneva G, Forouhar F, Carpenter Z, Ambesi-Impiombato A, Sánchez-Martín M, Kirschner-Schwabe R, Lew S, Seetharaman J, Tong L, Ferrando AA. Dieck CL, et al. Among authors: tong l. Cancer Cell. 2018 Jul 9;34(1):136-147.e6. doi: 10.1016/j.ccell.2018.06.003. Cancer Cell. 2018. PMID: 29990496 Free PMC article.

10

Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia.

Reglero C, Dieck CL, Zask A, Forouhar F, Laurent AP, Lin WW, Albero R, Miller HI, Ma C, Gastier-Foster JM, Loh ML, Tong L, Stockwell BR, Palomero T, Ferrando AA. Reglero C, et al. Among authors: tong l. Cancer Discov. 2022 Nov 2;12(11):2646-2665. doi: 10.1158/2159-8290.CD-22-0010. Cancer Discov. 2022. PMID: 35984649 Free PMC article.

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