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Page 1
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, Radaelli E, Tesseur I, Wray S, Ebneth A, Hardy J, Leroy K, Brion JP, Vanderhaeghen P, De Strooper B. Espuny-Camacho I, et al. Among authors: ebneth a. Neuron. 2017 Mar 8;93(5):1066-1081.e8. doi: 10.1016/j.neuron.2017.02.001. Epub 2017 Feb 23. Neuron. 2017. PMID: 28238547 Free article.
Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.
García-León JA, Cabrera-Socorro A, Eggermont K, Swijsen A, Terryn J, Fazal R, Nami F, Ordovás L, Quiles A, Lluis F, Serneels L, Wierda K, Sierksma A, Kreir M, Pestana F, Van Damme P, De Strooper B, Thorrez L, Ebneth A, Verfaillie CM. García-León JA, et al. Among authors: ebneth a. Alzheimers Dement. 2018 Oct;14(10):1261-1280. doi: 10.1016/j.jalz.2018.05.007. Epub 2018 Jul 20. Alzheimers Dement. 2018. PMID: 30036493 Free article.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Verheyen A, Diels A, Reumers J, Van Hoorde K, Van den Wyngaert I, van Outryve d'Ydewalle C, De Bondt A, Kuijlaars J, De Muynck L, De Hoogt R, Bretteville A, Jaensch S, Buist A, Cabrera-Socorro A, Wray S, Ebneth A, Roevens P, Royaux I, Peeters PJ. Verheyen A, et al. Among authors: ebneth a. Stem Cell Reports. 2018 Aug 14;11(2):363-379. doi: 10.1016/j.stemcr.2018.06.022. Epub 2018 Jul 26. Stem Cell Reports. 2018. PMID: 30057263 Free PMC article.
Development of a Scalable, High-Throughput-Compatible Assay to Detect Tau Aggregates Using iPSC-Derived Cortical Neurons Maintained in a Three-Dimensional Culture Format.
Medda X, Mertens L, Versweyveld S, Diels A, Barnham L, Bretteville A, Buist A, Verheyen A, Royaux I, Ebneth A, Cabrera-Socorro A. Medda X, et al. Among authors: ebneth a. J Biomol Screen. 2016 Sep;21(8):804-15. doi: 10.1177/1087057116638029. Epub 2016 Mar 16. J Biomol Screen. 2016. PMID: 26984927
Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.
Shih PY, Kreir M, Kumar D, Seibt F, Pestana F, Schmid B, Holst B, Clausen C, Steeg R, Fischer B, Pita-Almenar J, Ebneth A, Cabrera-Socorro A. Shih PY, et al. Among authors: ebneth a. Stem Cell Res. 2021 Jul;54:102386. doi: 10.1016/j.scr.2021.102386. Epub 2021 May 24. Stem Cell Res. 2021. PMID: 34229210 Free article.
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System.
Neyrinck K, Van Den Daele J, Vervliet T, De Smedt J, Wierda K, Nijs M, Vanbokhoven T, D'hondt A, Planque M, Fendt SM, Shih PY, Seibt F, Almenar JP, Kreir M, Kumar D, Broccoli V, Bultynck G, Ebneth A, Cabrera-Socorro A, Verfaillie C. Neyrinck K, et al. Among authors: ebneth a. Stem Cell Rev Rep. 2021 Oct;17(5):1855-1873. doi: 10.1007/s12015-021-10179-x. Epub 2021 May 12. Stem Cell Rev Rep. 2021. PMID: 33982246 Free PMC article.
Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease.
Schmid B, Holst B, Clausen C, Bahnassawy L, Reinhardt P, Bakker MHM, Díaz-Guerra E, Vicario C, Martino-Adami PV, Thoenes M, Ramirez A, Fliessbach K, Grezella C, Brüstle O, Peitz M, Ebneth A, Cabrera-Socorro A. Schmid B, et al. Among authors: ebneth a. Stem Cell Res. 2021 Apr;52:102180. doi: 10.1016/j.scr.2021.102180. Epub 2021 Feb 2. Stem Cell Res. 2021. PMID: 33556820 Free article.
Scalable expansion of iPSC and their derivatives across multiple lineages.
Kwok CK, Sébastien I, Hariharan K, Meiser I, Wihan J, Altmaier S, Karnatz I, Bauer D, Fischer B, Feile A, Cabrera-Socorro A, Rasmussen M, Holst B, Neubauer JC, Clausen C, Verfaillie C, Ebneth A, Hansson M, Steeg R, Zimmermann H. Kwok CK, et al. Among authors: ebneth a. Reprod Toxicol. 2022 Sep;112:23-35. doi: 10.1016/j.reprotox.2022.05.007. Epub 2022 May 17. Reprod Toxicol. 2022. PMID: 35595152 Free article.
The EBiSC iPSC bank for disease studies.
Steeg R, Neubauer JC, Müller SC, Ebneth A, Zimmermann H. Steeg R, et al. Among authors: ebneth a. Stem Cell Res. 2020 Dec;49:102034. doi: 10.1016/j.scr.2020.102034. Epub 2020 Oct 9. Stem Cell Res. 2020. PMID: 33099110 Free article.
45 results