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Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.
Woodham EF, Paul NR, Tyrrell B, Spence HJ, Swaminathan K, Scribner MR, Giampazolias E, Hedley A, Clark W, Kage F, Marston DJ, Hahn KM, Tait SW, Larue L, Brakebusch CH, Insall RH, Machesky LM. Woodham EF, et al. Among authors: brakebusch ch. Curr Biol. 2017 Mar 6;27(5):624-637. doi: 10.1016/j.cub.2017.01.033. Epub 2017 Feb 23. Curr Biol. 2017. PMID: 28238662 Free PMC article.
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
Block J, Breitsprecher D, Kühn S, Winterhoff M, Kage F, Geffers R, Duwe P, Rohn JL, Baum B, Brakebusch C, Geyer M, Stradal TE, Faix J, Rottner K. Block J, et al. Curr Biol. 2012 Jun 5;22(11):1005-12. doi: 10.1016/j.cub.2012.03.064. Epub 2012 May 17. Curr Biol. 2012. PMID: 22608513 Free PMC article.
Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Wang ZB, Jiang ZZ, Zhang QH, Hu MW, Huang L, Ou XH, Guo L, Ouyang YC, Hou Y, Brakebusch C, Schatten H, Sun QY. Wang ZB, et al. Mol Biol Cell. 2013 Dec;24(24):3832-41. doi: 10.1091/mbc.E13-03-0123. Epub 2013 Oct 16. Mol Biol Cell. 2013. PMID: 24131996 Free PMC article.
FMNL formins boost lamellipodial force generation.
Kage F, Winterhoff M, Dimchev V, Mueller J, Thalheim T, Freise A, Brühmann S, Kollasser J, Block J, Dimchev G, Geyer M, Schnittler HJ, Brakebusch C, Stradal TE, Carlier MF, Sixt M, Käs J, Faix J, Rottner K. Kage F, et al. Nat Commun. 2017 Mar 22;8:14832. doi: 10.1038/ncomms14832. Nat Commun. 2017. PMID: 28327544 Free PMC article.
183 results