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Development of 1,2,4-Oxadiazoles as Potent and Selective Inhibitors of the Human Deacetylase Sirtuin 2: Structure-Activity Relationship, X-ray Crystal Structure, and Anticancer Activity.
Moniot S, Forgione M, Lucidi A, Hailu GS, Nebbioso A, Carafa V, Baratta F, Altucci L, Giacché N, Passeri D, Pellicciari R, Mai A, Steegborn C, Rotili D. Moniot S, et al. Among authors: forgione m. J Med Chem. 2017 Mar 23;60(6):2344-2360. doi: 10.1021/acs.jmedchem.6b01609. Epub 2017 Mar 14. J Med Chem. 2017. PMID: 28240897
Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones.
Nawrozkij MB, Forgione M, Yablokov AS, Lucidi A, Tomaselli D, Patsilinakos A, Panella C, Hailu GS, Kirillov IA, Badia R, Riveira-Muñoz E, Crespan E, Armijos Rivera JI, Cirilli R, Ragno R, Esté JA, Maga G, Mai A, Rotili D. Nawrozkij MB, et al. Among authors: forgione m. J Med Chem. 2019 Jan 24;62(2):604-621. doi: 10.1021/acs.jmedchem.8b01238. Epub 2018 Dec 20. J Med Chem. 2019. PMID: 30525601
Sirtuin functions and modulation: from chemistry to the clinic.
Carafa V, Rotili D, Forgione M, Cuomo F, Serretiello E, Hailu GS, Jarho E, Lahtela-Kakkonen M, Mai A, Altucci L. Carafa V, et al. Among authors: forgione m. Clin Epigenetics. 2016 May 25;8:61. doi: 10.1186/s13148-016-0224-3. eCollection 2016. Clin Epigenetics. 2016. PMID: 27226812 Free PMC article. Review.
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Speranzini V, Rotili D, Ciossani G, Pilotto S, Marrocco B, Forgione M, Lucidi A, Forneris F, Mehdipour P, Velankar S, Mai A, Mattevi A. Speranzini V, et al. Among authors: forgione m. Sci Adv. 2016 Sep 9;2(9):e1601017. doi: 10.1126/sciadv.1601017. eCollection 2016 Sep. Sci Adv. 2016. PMID: 27626075 Free PMC article.
Molecular basis of bacterial lectin recognition of eukaryotic glycans: The case of Mycoplasma pneumoniae and Mycoplasma genitalium cytoadhesins.
Marseglia A, Forgione MC, Marcos-Silva M, Di Carluccio C, Manabe Y, Vizarraga D, Nieto-Fabregat F, Lenza MP, Fukase K, Molinaro A, Pich OQ, Aparicio D, Silipo A, Marchetti R. Marseglia A, et al. Among authors: forgione mc. Int J Biol Macromol. 2024 Nov;279(Pt 2):135277. doi: 10.1016/j.ijbiomac.2024.135277. Epub 2024 Sep 1. Int J Biol Macromol. 2024. PMID: 39226978 Free article.
57 results