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Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial.
Snowdon VK, Lachlan NJ, Hoy AM, Hadoke PW, Semple SI, Patel D, Mungall W, Kendall TJ, Thomson A, Lennen RJ, Jansen MA, Moran CM, Pellicoro A, Ramachandran P, Shaw I, Aucott RL, Severin T, Saini R, Pak J, Yates D, Dongre N, Duffield JS, Webb DJ, Iredale JP, Hayes PC, Fallowfield JA. Snowdon VK, et al. Among authors: shaw i. PLoS Med. 2017 Feb 28;14(2):e1002248. doi: 10.1371/journal.pmed.1002248. eCollection 2017 Feb. PLoS Med. 2017. PMID: 28245243 Free PMC article. Clinical Trial.
Human kidney pericytes produce renin.
Stefanska A, Kenyon C, Christian HC, Buckley C, Shaw I, Mullins JJ, Péault B. Stefanska A, et al. Among authors: shaw i. Kidney Int. 2016 Dec;90(6):1251-1261. doi: 10.1016/j.kint.2016.07.035. Epub 2016 Sep 24. Kidney Int. 2016. PMID: 27678158 Free PMC article.
Encompassing view of spatial and single-cell RNA sequencing renews the role of the microvasculature in human atherosclerosis.
Bleckwehl T, Babler A, Tebens M, Maryam S, Nyberg M, Bosteen M, Halder M, Shaw I, Fleig S, Pyke C, Hvid H, Voetmann LM, van Buul JD, Sluimer JC, Das V, Baumgart S, Kramann R, Hayat S. Bleckwehl T, et al. Among authors: shaw i. Nat Cardiovasc Res. 2024 Dec 23. doi: 10.1038/s44161-024-00582-1. Online ahead of print. Nat Cardiovasc Res. 2024. PMID: 39715784
355 results