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A Proposal to Redefine Clinical Immunogenicity Assessment.
Mytych DT, Hock MB, Kroenke M, Jawa V, Kaliyaperumal A, Zhou Y. Mytych DT, et al. Among authors: hock mb. AAPS J. 2017 May;19(3):599-602. doi: 10.1208/s12248-017-0059-7. Epub 2017 Feb 28. AAPS J. 2017. PMID: 28247192
Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.
Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ. Moffat GJ, et al. Among authors: hock mb. Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):178-88. doi: 10.1002/bdrb.21105. Birth Defects Res B Dev Reprod Toxicol. 2014. PMID: 24753333
Clinical Pharmacokinetics and Pharmacodynamics of Etelcalcetide, a Novel Calcimimetic for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis.
Wu B, Melhem M, Subramanian R, Chen P, Jaramilla Sloey B, Fouqueray B, Hock MB, Skiles GL, Chow AT, Lee E. Wu B, et al. Among authors: hock mb. J Clin Pharmacol. 2018 Jun;58(6):717-726. doi: 10.1002/jcph.1090. Epub 2018 Mar 13. J Clin Pharmacol. 2018. PMID: 29534286 Review.
Pharmacokinetics, Biotransformation, and Excretion of [14C]Etelcalcetide (AMG 416) Following a Single Microtracer Intravenous Dose in Patients with Chronic Kidney Disease on Hemodialysis.
Subramanian R, Zhu X, Hock MB, Sloey BJ, Wu B, Wilson SF, Egbuna O, Slatter JG, Xiao J, Skiles GL. Subramanian R, et al. Among authors: hock mb. Clin Pharmacokinet. 2017 Feb;56(2):179-192. doi: 10.1007/s40262-016-0433-0. Clin Pharmacokinet. 2017. PMID: 27517676 Free PMC article. Clinical Trial.
Immunogenicity/hypersensitivity of biologics.
Leach MW, Rottman JB, Hock MB, Finco D, Rojko JL, Beyer JC. Leach MW, et al. Among authors: hock mb. Toxicol Pathol. 2014 Jan;42(1):293-300. doi: 10.1177/0192623313510987. Epub 2013 Nov 14. Toxicol Pathol. 2014. PMID: 24240973
24 results