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PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis.
Hirabayashi T, Anjo T, Kaneko A, Senoo Y, Shibata A, Takama H, Yokoyama K, Nishito Y, Ono T, Taya C, Muramatsu K, Fukami K, Muñoz-Garcia A, Brash AR, Ikeda K, Arita M, Akiyama M, Murakami M. Hirabayashi T, et al. Among authors: ikeda k. Nat Commun. 2017 Mar 1;8:14609. doi: 10.1038/ncomms14609. Nat Commun. 2017. PMID: 28248300 Free PMC article.
Hair follicular expression and function of group X secreted phospholipase A2 in mouse skin.
Yamamoto K, Taketomi Y, Isogai Y, Miki Y, Sato H, Masuda S, Nishito Y, Morioka K, Ishimoto Y, Suzuki N, Yokota Y, Hanasaki K, Ishikawa Y, Ishii T, Kobayashi T, Fukami K, Ikeda K, Nakanishi H, Taguchi R, Murakami M. Yamamoto K, et al. Among authors: ikeda k. J Biol Chem. 2011 Apr 1;286(13):11616-31. doi: 10.1074/jbc.M110.206714. Epub 2011 Jan 25. J Biol Chem. 2011. PMID: 21266583 Free PMC article.
Analysis of two major intracellular phospholipases A(2) (PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts.
Ueno N, Taketomi Y, Yamamoto K, Hirabayashi T, Kamei D, Kita Y, Shimizu T, Shinzawa K, Tsujimoto Y, Ikeda K, Taguchi R, Murakami M. Ueno N, et al. Among authors: ikeda k. J Biol Chem. 2011 Oct 28;286(43):37249-63. doi: 10.1074/jbc.M111.290312. Epub 2011 Aug 31. J Biol Chem. 2011. PMID: 21880721 Free PMC article.
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Taketomi Y, Ueno N, Kojima T, Sato H, Murase R, Yamamoto K, Tanaka S, Sakanaka M, Nakamura M, Nishito Y, Kawana M, Kambe N, Ikeda K, Taguchi R, Nakamizo S, Kabashima K, Gelb MH, Arita M, Yokomizo T, Nakamura M, Watanabe K, Hirai H, Nakamura M, Okayama Y, Ra C, Aritake K, Urade Y, Morimoto K, Sugimoto Y, Shimizu T, Narumiya S, Hara S, Murakami M. Taketomi Y, et al. Among authors: ikeda k. Nat Immunol. 2013 Jun;14(6):554-63. doi: 10.1038/ni.2586. Epub 2013 Apr 28. Nat Immunol. 2013. PMID: 23624557 Free PMC article.
Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer's disease.
Tajima Y, Ishikawa M, Maekawa K, Murayama M, Senoo Y, Nishimaki-Mogami T, Nakanishi H, Ikeda K, Arita M, Taguchi R, Okuno A, Mikawa R, Niida S, Takikawa O, Saito Y. Tajima Y, et al. Among authors: ikeda k. Lipids Health Dis. 2013 May 9;12:68. doi: 10.1186/1476-511X-12-68. Lipids Health Dis. 2013. PMID: 23659495 Free PMC article.
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators.
Miki Y, Yamamoto K, Taketomi Y, Sato H, Shimo K, Kobayashi T, Ishikawa Y, Ishii T, Nakanishi H, Ikeda K, Taguchi R, Kabashima K, Arita M, Arai H, Lambeau G, Bollinger JM, Hara S, Gelb MH, Murakami M. Miki Y, et al. Among authors: ikeda k. J Exp Med. 2013 Jun 3;210(6):1217-34. doi: 10.1084/jem.20121887. Epub 2013 May 20. J Exp Med. 2013. PMID: 23690440 Free PMC article.
The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity.
Sato H, Taketomi Y, Ushida A, Isogai Y, Kojima T, Hirabayashi T, Miki Y, Yamamoto K, Nishito Y, Kobayashi T, Ikeda K, Taguchi R, Hara S, Ida S, Miyamoto Y, Watanabe M, Baba H, Miyata K, Oike Y, Gelb MH, Murakami M. Sato H, et al. Among authors: ikeda k. Cell Metab. 2014 Jul 1;20(1):119-32. doi: 10.1016/j.cmet.2014.05.002. Epub 2014 Jun 5. Cell Metab. 2014. PMID: 24910243 Free PMC article.
The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia.
Yamamoto K, Miki Y, Sato M, Taketomi Y, Nishito Y, Taya C, Muramatsu K, Ikeda K, Nakanishi H, Taguchi R, Kambe N, Kabashima K, Lambeau G, Gelb MH, Murakami M. Yamamoto K, et al. Among authors: ikeda k. J Exp Med. 2015 Oct 19;212(11):1901-19. doi: 10.1084/jem.20141904. Epub 2015 Oct 5. J Exp Med. 2015. PMID: 26438362 Free PMC article.
7,200 results