Bonomo RA - Search Results

1

Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic Fibrosis Patients.

Papp-Wallace KM, Becka SA, Zeiser ET, Ohuchi N, Mojica MF, Gatta JA, Falleni M, Tosi D, Borghi E, Winkler ML, Wilson BM, LiPuma JJ, Nukaga M, Bonomo RA. Papp-Wallace KM, et al. Among authors: bonomo ra. ACS Infect Dis. 2017 Jul 14;3(7):502-511. doi: 10.1021/acsinfecdis.7b00020. Epub 2017 Mar 30. ACS Infect Dis. 2017. PMID: 28264560 Free PMC article.

2

Molecular genetics of resistance to both ceftazidime and beta-lactam-beta-lactamase inhibitor combinations in Klebsiella pneumoniae and in vivo response to beta-lactam therapy.

Rice LB, Carias LL, Bonomo RA, Shlaes DM. Rice LB, et al. Among authors: bonomo ra. J Infect Dis. 1996 Jan;173(1):151-8. doi: 10.1093/infdis/173.1.151. J Infect Dis. 1996. PMID: 8537652

3

Structure of the SHV-1 beta-lactamase.

Kuzin AP, Nukaga M, Nukaga Y, Hujer AM, Bonomo RA, Knox JR. Kuzin AP, et al. Among authors: bonomo ra. Biochemistry. 1999 May 4;38(18):5720-7. doi: 10.1021/bi990136d. Biochemistry. 1999. PMID: 10231522

4

Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam.

Kuzin AP, Nukaga M, Nukaga Y, Hujer A, Bonomo RA, Knox JR. Kuzin AP, et al. Among authors: bonomo ra. Biochemistry. 2001 Feb 13;40(6):1861-6. doi: 10.1021/bi0022745. Biochemistry. 2001. PMID: 11327849

5

Ultrahigh resolution structure of a class A beta-lactamase: on the mechanism and specificity of the extended-spectrum SHV-2 enzyme.

Nukaga M, Mayama K, Hujer AM, Bonomo RA, Knox JR. Nukaga M, et al. Among authors: bonomo ra. J Mol Biol. 2003 Apr 18;328(1):289-301. doi: 10.1016/s0022-2836(03)00210-9. J Mol Biol. 2003. PMID: 12684014

6

Inhibition of class A and class C beta-lactamases by penems: crystallographic structures of a novel 1,4-thiazepine intermediate.

Nukaga M, Abe T, Venkatesan AM, Mansour TS, Bonomo RA, Knox JR. Nukaga M, et al. Among authors: bonomo ra. Biochemistry. 2003 Nov 18;42(45):13152-9. doi: 10.1021/bi034986b. Biochemistry. 2003. PMID: 14609325

7

Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition.

Bethel CR, Hujer AM, Helfand MS, Bonomo RA. Bethel CR, et al. Among authors: bonomo ra. FEMS Microbiol Lett. 2004 May 1;234(1):99-103. doi: 10.1016/j.femsle.2004.03.025. FEMS Microbiol Lett. 2004. PMID: 15109726

8

Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates.

Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR. Venkatesan AM, et al. Among authors: bonomo ra. J Med Chem. 2004 Dec 16;47(26):6556-68. doi: 10.1021/jm049680x. J Med Chem. 2004. PMID: 15588091

9

ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates.

Endimiani A, Hujer KM, Hujer AM, Armstrong ES, Choudhary Y, Aggen JB, Bonomo RA. Endimiani A, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2009 Oct;53(10):4504-7. doi: 10.1128/AAC.00556-09. Antimicrob Agents Chemother. 2009. PMID: 19770287 Free PMC article.

10

Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.

Papp-Wallace KM, Bethel CR, Distler AM, Kasuboski C, Taracila M, Bonomo RA. Papp-Wallace KM, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2010 Feb;54(2):890-7. doi: 10.1128/AAC.00693-09. Epub 2009 Dec 14. Antimicrob Agents Chemother. 2010. PMID: 20008772 Free PMC article.

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