Lin W - Search Results

1

Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug.

He H, Tran P, Gu H, Tedesco V, Zhang J, Lin W, Gatlik E, Klein K, Heimbach T. He H, et al. Among authors: lin w. Drug Metab Dispos. 2017 May;45(5):540-555. doi: 10.1124/dmd.116.072744. Epub 2017 Mar 7. Drug Metab Dispos. 2017. PMID: 28270565

2

Pharmacokinetics of dietary cancer chemopreventive compound dibenzoylmethane in rats and the impact of nanoemulsion and genetic knockout of Nrf2 on its disposition.

Lin W, Hong JL, Shen G, Wu RT, Wang Y, Huang MT, Newmark HL, Huang Q, Khor TO, Heimbach T, Kong AN. Lin W, et al. Biopharm Drug Dispos. 2011 Mar;32(2):65-75. doi: 10.1002/bdd.734. Epub 2010 Dec 16. Biopharm Drug Dispos. 2011. PMID: 21341276 Free PMC article.

3

Prospective Predictions of Human Pharmacokinetics for Eighteen Compounds.

Zhang T, Heimbach T, Lin W, Zhang J, He H. Zhang T, et al. Among authors: lin w. J Pharm Sci. 2015 Sep;104(9):2795-806. doi: 10.1002/jps.24373. Epub 2015 Feb 17. J Pharm Sci. 2015. PMID: 25690565

4

Clinical Exposure Boost Predictions by Integrating Cytochrome P450 3A4-Humanized Mouse Studies With PBPK Modeling.

Zhang J, Heimbach T, Scheer N, Barve A, Li W, Lin W, He H. Zhang J, et al. Among authors: lin w. J Pharm Sci. 2016 Apr;105(4):1398-404. doi: 10.1016/j.xphs.2016.01.021. J Pharm Sci. 2016. PMID: 27019957

5

A Physiologically Based Pharmacokinetic Model to Describe Artemether Pharmacokinetics in Adult and Pediatric Patients.

Lin W, Heimbach T, Jain JP, Awasthi R, Hamed K, Sunkara G, He H. Lin W, et al. J Pharm Sci. 2016 Oct;105(10):3205-3213. doi: 10.1016/j.xphs.2016.06.026. Epub 2016 Aug 6. J Pharm Sci. 2016. PMID: 27506269 Free article.

6

Pharmacokinetics, Distribution, Metabolism, and Excretion of Omadacycline following a Single Intravenous or Oral Dose of 14C-Omadacycline in Rats.

Lin W, Flarakos J, Du Y, Hu W, He H, Mangold J, Tanaka SK, Villano S. Lin W, et al. Antimicrob Agents Chemother. 2016 Dec 27;61(1):e01784-16. doi: 10.1128/AAC.01784-16. Print 2017 Jan. Antimicrob Agents Chemother. 2016. PMID: 27821446 Free PMC article.

7

Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model.

Lin W, Ji T, Einolf H, Ayalasomayajula S, Lin TH, Hanna I, Heimbach T, Breen C, Jarugula V, He H. Lin W, et al. Among authors: lin th. J Pharm Sci. 2017 May;106(5):1439-1451. doi: 10.1016/j.xphs.2017.01.007. Epub 2017 Jan 13. J Pharm Sci. 2017. PMID: 28089685

8

Food effects in paediatric medicines development for products Co-administered with food.

Batchelor H, Kaukonen AM, Klein S, Davit B, Ju R, Ternik R, Heimbach T, Lin W, Wang J, Storey D. Batchelor H, et al. Among authors: lin w. Int J Pharm. 2018 Feb 5;536(2):530-535. doi: 10.1016/j.ijpharm.2017.05.011. Epub 2017 May 8. Int J Pharm. 2018. PMID: 28495584 Free article.

9

Physiologically Based Pharmacokinetic Model Predictions of Panobinostat (LBH589) as a Victim and Perpetrator of Drug-Drug Interactions.

Einolf HJ, Lin W, Won CS, Wang L, Gu H, Chun DY, He H, Mangold JB. Einolf HJ, et al. Among authors: lin w. Drug Metab Dispos. 2017 Dec;45(12):1304-1316. doi: 10.1124/dmd.117.076851. Epub 2017 Sep 14. Drug Metab Dispos. 2017. PMID: 28912253

10

Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients.

Heimbach T, Lin W, Hourcade-Potelleret F, Tian X, Combes FP, Horvath N, He H. Heimbach T, et al. Among authors: lin w. J Pharm Sci. 2019 Jun;108(6):2191-2198. doi: 10.1016/j.xphs.2019.01.028. Epub 2019 Feb 2. J Pharm Sci. 2019. PMID: 30721710

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