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Page 1
Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer.
Dreijerink KMA, Groner AC, Vos ESM, Font-Tello A, Gu L, Chi D, Reyes J, Cook J, Lim E, Lin CY, de Laat W, Rao PK, Long HW, Brown M. Dreijerink KMA, et al. Among authors: de laat w. Cell Rep. 2017 Mar 7;18(10):2359-2372. doi: 10.1016/j.celrep.2017.02.025. Cell Rep. 2017. PMID: 28273452 Free PMC article.
eRNAs are required for p53-dependent enhancer activity and gene transcription.
Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. Melo CA, et al. Among authors: de laat w, de wit e. Mol Cell. 2013 Feb 7;49(3):524-35. doi: 10.1016/j.molcel.2012.11.021. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273978 Free article.
A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia.
Gröschel S, Sanders MA, Hoogenboezem R, de Wit E, Bouwman BAM, Erpelinck C, van der Velden VHJ, Havermans M, Avellino R, van Lom K, Rombouts EJ, van Duin M, Döhner K, Beverloo HB, Bradner JE, Döhner H, Löwenberg B, Valk PJM, Bindels EMJ, de Laat W, Delwel R. Gröschel S, et al. Among authors: de laat w, de wit e. Cell. 2014 Apr 10;157(2):369-381. doi: 10.1016/j.cell.2014.02.019. Epub 2014 Apr 3. Cell. 2014. PMID: 24703711 Free article.
Large-scale identification of coregulated enhancer networks in the adult human brain.
Vermunt MW, Reinink P, Korving J, de Bruijn E, Creyghton PM, Basak O, Geeven G, Toonen PW, Lansu N, Meunier C, van Heesch S; Netherlands Brain Bank; Clevers H, de Laat W, Cuppen E, Creyghton MP. Vermunt MW, et al. Among authors: de laat w, de bruijn e. Cell Rep. 2014 Oct 23;9(2):767-79. doi: 10.1016/j.celrep.2014.09.023. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373911 Free article.
A Long-Distance Chromatin Affair.
Denker A, de Laat W. Denker A, et al. Among authors: de laat w. Cell. 2015 Aug 27;162(5):942-3. doi: 10.1016/j.cell.2015.08.022. Cell. 2015. PMID: 26317462 Free article.
YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers.
Galli GG, Carrara M, Yuan WC, Valdes-Quezada C, Gurung B, Pepe-Mooney B, Zhang T, Geeven G, Gray NS, de Laat W, Calogero RA, Camargo FD. Galli GG, et al. Among authors: de laat w. Mol Cell. 2015 Oct 15;60(2):328-37. doi: 10.1016/j.molcel.2015.09.001. Epub 2015 Oct 1. Mol Cell. 2015. PMID: 26439301 Free PMC article.
CTCF Binding Polarity Determines Chromatin Looping.
de Wit E, Vos ES, Holwerda SJ, Valdes-Quezada C, Verstegen MJ, Teunissen H, Splinter E, Wijchers PJ, Krijger PH, de Laat W. de Wit E, et al. Among authors: de laat w. Mol Cell. 2015 Nov 19;60(4):676-84. doi: 10.1016/j.molcel.2015.09.023. Epub 2015 Oct 29. Mol Cell. 2015. PMID: 26527277 Free article.
Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination.
Austenaa LM, Barozzi I, Simonatto M, Masella S, Della Chiara G, Ghisletti S, Curina A, de Wit E, Bouwman BA, de Pretis S, Piccolo V, Termanini A, Prosperini E, Pelizzola M, de Laat W, Natoli G. Austenaa LM, et al. Among authors: de laat w, de pretis s, de wit e. Mol Cell. 2015 Nov 5;60(3):460-74. doi: 10.1016/j.molcel.2015.09.018. Epub 2015 Oct 22. Mol Cell. 2015. PMID: 26593720 Free article.
140 results