Gu G - Search Results

1

Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.

Petrenko V, Saini C, Giovannoni L, Gobet C, Sage D, Unser M, Heddad Masson M, Gu G, Bosco D, Gachon F, Philippe J, Dibner C. Petrenko V, et al. Among authors: gu g. Genes Dev. 2017 Feb 15;31(4):383-398. doi: 10.1101/gad.290379.116. Epub 2017 Mar 8. Genes Dev. 2017. PMID: 28275001 Free PMC article.

2

Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse.

Wang S, Zhang J, Zhao A, Hipkens S, Magnuson MA, Gu G. Wang S, et al. Among authors: gu g. Mech Dev. 2007 Nov-Dec;124(11-12):898-910. doi: 10.1016/j.mod.2007.08.004. Epub 2007 Sep 4. Mech Dev. 2007. PMID: 17928203 Free PMC article.

3

Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells.

Zhao A, Ohara-Imaizumi M, Brissova M, Benninger RK, Xu Y, Hao Y, Abramowitz J, Boulay G, Powers AC, Piston D, Jiang M, Nagamatsu S, Birnbaumer L, Gu G. Zhao A, et al. Among authors: gu g. Diabetes. 2010 Oct;59(10):2522-9. doi: 10.2337/db09-1719. Epub 2010 Jul 9. Diabetes. 2010. PMID: 20622165 Free PMC article.

4

Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells.

Zhu X, Hu R, Brissova M, Stein RW, Powers AC, Gu G, Kaverina I. Zhu X, et al. Among authors: gu g. Dev Cell. 2015 Sep 28;34(6):656-68. doi: 10.1016/j.devcel.2015.08.020. Dev Cell. 2015. PMID: 26418295 Free PMC article.

5

Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca²⁺ Sensitivity of Insulin Secretion Vesicles.

Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ Jr, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G. Huang C, et al. Among authors: gu g. Dev Cell. 2018 May 7;45(3):347-361.e5. doi: 10.1016/j.devcel.2018.03.013. Epub 2018 Apr 12. Dev Cell. 2018. PMID: 29656931 Free PMC article.

6

A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development.

Osipovich AB, Dudek KD, Greenfest-Allen E, Cartailler JP, Manduchi E, Potter Case L, Choi E, Chapman AG, Clayton HW, Gu G, Stoeckert CJ Jr, Magnuson MA. Osipovich AB, et al. Among authors: gu g. Development. 2021 Mar 21;148(6):dev196964. doi: 10.1242/dev.196964. Development. 2021. PMID: 33653874 Free PMC article.

7

Microtubules and Gαo-signaling modulate the preferential secretion of young insulin secretory granules in islet β cells via independent pathways.

Hu R, Zhu X, Yuan M, Ho KH, Kaverina I, Gu G. Hu R, et al. Among authors: gu g. PLoS One. 2021 Jul 22;16(7):e0241939. doi: 10.1371/journal.pone.0241939. eCollection 2021. PLoS One. 2021. PMID: 34292976 Free PMC article.

8

Microtubules regulate pancreatic β-cell heterogeneity via spatiotemporal control of insulin secretion hot spots.

Trogden KP, Lee J, Bracey KM, Ho KH, McKinney H, Zhu X, Arpag G, Folland TG, Osipovich AB, Magnuson MA, Zanic M, Gu G, Holmes WR, Kaverina I. Trogden KP, et al. Among authors: gu g. Elife. 2021 Nov 16;10:e59912. doi: 10.7554/eLife.59912. Elife. 2021. PMID: 34783306 Free PMC article.

9

Global expression analysis of gene regulatory pathways during endocrine pancreatic development.

Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B, Melton DA. Gu G, et al. Development. 2004 Jan;131(1):165-79. doi: 10.1242/dev.00921. Epub 2003 Dec 3. Development. 2004. PMID: 14660441

10

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function.

Wang S, Jensen JN, Seymour PA, Hsu W, Dor Y, Sander M, Magnuson MA, Serup P, Gu G. Wang S, et al. Among authors: gu g. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9715-20. doi: 10.1073/pnas.0904247106. Epub 2009 Jun 1. Proc Natl Acad Sci U S A. 2009. PMID: 19487660 Free PMC article.

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