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Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.
Shen Y, Wang Y, Chen T, Gao F, Gong J, Abramczyk D, Walker R, Zhao H, Chen S, Liu W, Luo Y, Müller CA, Paul-Dubois-Taine A, Alver B, Stracquadanio G, Mitchell LA, Luo Z, Fan Y, Zhou B, Wen B, Tan F, Wang Y, Zi J, Xie Z, Li B, Yang K, Richardson SM, Jiang H, French CE, Nieduszynski CA, Koszul R, Marston AL, Yuan Y, Wang J, Bader JS, Dai J, Boeke JD, Xu X, Cai Y, Yang H. Shen Y, et al. Among authors: chen s, chen t. Science. 2017 Mar 10;355(6329):eaaf4791. doi: 10.1126/science.aaf4791. Science. 2017. PMID: 28280153 Free PMC article.
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.
Shen Y, Stracquadanio G, Wang Y, Yang K, Mitchell LA, Xue Y, Cai Y, Chen T, Dymond JS, Kang K, Gong J, Zeng X, Zhang Y, Li Y, Feng Q, Xu X, Wang J, Wang J, Yang H, Boeke JD, Bader JS. Shen Y, et al. Among authors: chen t. Genome Res. 2016 Jan;26(1):36-49. doi: 10.1101/gr.193433.115. Epub 2015 Nov 13. Genome Res. 2016. PMID: 26566658 Free PMC article.
Systematical Engineering of Synthetic Yeast for Enhanced Production of Lycopene.
Zhang Y, Chiu TY, Zhang JT, Wang SJ, Wang SW, Liu LY, Ping Z, Wang Y, Chen A, Zhang WW, Chen T, Wang Y, Shen Y. Zhang Y, et al. Among authors: chen a, chen t. Bioengineering (Basel). 2021 Jan 19;8(1):14. doi: 10.3390/bioengineering8010014. Bioengineering (Basel). 2021. PMID: 33477926 Free PMC article.
Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast.
Shen Y, Gao F, Wang Y, Wang Y, Zheng J, Gong J, Zhang J, Luo Z, Schindler D, Deng Y, Ding W, Lin T, Swidah R, Zhao H, Jiang S, Zeng C, Chen S, Chen T, Wang Y, Luo Y, Mitchell L, Bader JS, Zhang G, Shen X, Wang J, Fu X, Dai J, Boeke JD, Yang H, Xu X, Cai Y. Shen Y, et al. Among authors: chen s, chen t. Cell Genom. 2023 Nov 9;3(11):100364. doi: 10.1016/j.xgen.2023.100364. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020968 Free PMC article.
Towards practical and robust DNA-based data archiving using the yin-yang codec system.
Ping Z, Chen S, Zhou G, Huang X, Zhu SJ, Zhang H, Lee HH, Lan Z, Cui J, Chen T, Zhang W, Yang H, Xu X, Church GM, Shen Y. Ping Z, et al. Among authors: chen s, chen t. Nat Comput Sci. 2022 Apr;2(4):234-242. doi: 10.1038/s43588-022-00231-2. Epub 2022 Apr 25. Nat Comput Sci. 2022. PMID: 38177542 Free PMC article.
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