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Tudor, MBT and chromo domains gauge the degree of lysine methylation.
Kim J, Daniel J, Espejo A, Lake A, Krishna M, Xia L, Zhang Y, Bedford MT. Kim J, et al. Among authors: bedford mt. EMBO Rep. 2006 Apr;7(4):397-403. doi: 10.1038/sj.embor.7400625. Epub 2006 Jan 13. EMBO Rep. 2006. PMID: 16415788 Free PMC article.
Histone arginine methylation.
Di Lorenzo A, Bedford MT. Di Lorenzo A, et al. Among authors: bedford mt. FEBS Lett. 2011 Jul 7;585(13):2024-31. doi: 10.1016/j.febslet.2010.11.010. Epub 2010 Nov 11. FEBS Lett. 2011. PMID: 21074527 Free PMC article. Review.
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.
Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD. Rothbart SB, et al. Among authors: bedford mt. Nat Struct Mol Biol. 2012 Nov;19(11):1155-60. doi: 10.1038/nsmb.2391. Epub 2012 Sep 30. Nat Struct Mol Biol. 2012. PMID: 23022729 Free PMC article.
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
James LI, Barsyte-Lovejoy D, Zhong N, Krichevsky L, Korboukh VK, Herold JM, MacNevin CJ, Norris JL, Sagum CA, Tempel W, Marcon E, Guo H, Gao C, Huang XP, Duan S, Emili A, Greenblatt JF, Kireev DB, Jin J, Janzen WP, Brown PJ, Bedford MT, Arrowsmith CH, Frye SV. James LI, et al. Among authors: bedford mt. Nat Chem Biol. 2013 Mar;9(3):184-91. doi: 10.1038/nchembio.1157. Epub 2013 Jan 6. Nat Chem Biol. 2013. PMID: 23292653 Free PMC article.
Readers of histone methylarginine marks.
Gayatri S, Bedford MT. Gayatri S, et al. Among authors: bedford mt. Biochim Biophys Acta. 2014 Aug;1839(8):702-10. doi: 10.1016/j.bbagrm.2014.02.015. Epub 2014 Feb 28. Biochim Biophys Acta. 2014. PMID: 24583552 Free PMC article. Review.
Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor.
Carr SM, Munro S, Zalmas LP, Fedorov O, Johansson C, Krojer T, Sagum CA, Bedford MT, Oppermann U, La Thangue NB. Carr SM, et al. Among authors: bedford mt. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11341-6. doi: 10.1073/pnas.1403737111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049398 Free PMC article.
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
Stuckey JI, Dickson BM, Cheng N, Liu Y, Norris JL, Cholensky SH, Tempel W, Qin S, Huber KG, Sagum C, Black K, Li F, Huang XP, Roth BL, Baughman BM, Senisterra G, Pattenden SG, Vedadi M, Brown PJ, Bedford MT, Min J, Arrowsmith CH, James LI, Frye SV. Stuckey JI, et al. Among authors: bedford mt. Nat Chem Biol. 2016 Mar;12(3):180-7. doi: 10.1038/nchembio.2007. Epub 2016 Jan 25. Nat Chem Biol. 2016. PMID: 26807715 Free PMC article.
226 results