Elgart A - Search Results

1

A population pharmacokinetic meta-analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects.

Edwards AY, Elgart A, Farrell C, Barnett-Griness O, Rabinovich-Guilatt L, Spiegelstein O. Edwards AY, et al. Among authors: elgart a. Br J Clin Pharmacol. 2017 Sep;83(9):1932-1943. doi: 10.1111/bcp.13287. Epub 2017 May 2. Br J Clin Pharmacol. 2017. PMID: 28294391 Free PMC article.

2

Impact of dosing regimen of custirsen, an antisense oligonucleotide, on safety, tolerability and cardiac repolarization in healthy subjects.

Rabinovich-Guilatt L, Elgart A, Erisson L, Willsie SK, Tessler S, Barnett-Griness O, Pande A, Spiegelstein O. Rabinovich-Guilatt L, et al. Among authors: elgart a. Br J Clin Pharmacol. 2015 Sep;80(3):436-45. doi: 10.1111/bcp.12633. Epub 2015 Jun 22. Br J Clin Pharmacol. 2015. PMID: 25782535 Free PMC article. Clinical Trial.

3

A Thorough QT/QTc Study With Laquinimod, a Novel Immunomodulator in Development for Multiple Sclerosis and Huntington Disease.

Spiegelstein O, Mimrod D, Rabinovich L, Eyal E, Sprenger C, Elgart A, Samara E, Morganroth J. Spiegelstein O, et al. Among authors: elgart a. Clin Pharmacol Drug Dev. 2019 Jan;8(1):49-59. doi: 10.1002/cpdd.442. Epub 2018 May 22. Clin Pharmacol Drug Dev. 2019. PMID: 29786964 Clinical Trial.

4

The effect of laquinimod, a novel immuno-modulator in development to treat Huntington disease, on the pharmacokinetics of ethinylestradiol and levonorgestrel in healthy young women.

Elgart A, Zur AA, Mimrod D, Dror V, Bar-Ilan O, Korver T, Spiegelstein O. Elgart A, et al. Eur J Clin Pharmacol. 2019 Jan;75(1):41-49. doi: 10.1007/s00228-018-2549-7. Epub 2018 Sep 6. Eur J Clin Pharmacol. 2019. PMID: 30191262 Clinical Trial.

5

Pharmacokinetics and safety of single and multiple doses of rasagiline in healthy Japanese and caucasian subjects.

Elgart A, Rabinovich-Guilatt L, Eyal E, Gross A, Spiegelstein O. Elgart A, et al. Basic Clin Pharmacol Toxicol. 2019 Mar;124(3):273-284. doi: 10.1111/bcpt.13131. Epub 2018 Oct 21. Basic Clin Pharmacol Toxicol. 2019. PMID: 30218626 Free article. Clinical Trial.

6

The Effect of CYP3A Induction and Inhibition on the Pharmacokinetics of Laquinimod, a Novel Neuroimmunomodulator.

Elgart A, Greenblatt DJ, Loupe PS, Zur AA, Weiss S, Mimrod D, Spiegelstein O. Elgart A, et al. Clin Pharmacol Drug Dev. 2020 Nov;9(8):1015-1024. doi: 10.1002/cpdd.785. Epub 2020 Apr 1. Clin Pharmacol Drug Dev. 2020. PMID: 32237115

7

Population Pharmacokinetic Modeling and Simulation of TV-46000: A Long-Acting Injectable Formulation of Risperidone.

Perlstein I, Merenlender Wagner A, Gomeni R, Lamson M, Harary E, Spiegelstein O, Kalmanczhelyi A, Tiver R, Loupe P, Levi M, Elgart A. Perlstein I, et al. Among authors: elgart a. Clin Pharmacol Drug Dev. 2022 Jul;11(7):865-877. doi: 10.1002/cpdd.1078. Epub 2022 Mar 4. Clin Pharmacol Drug Dev. 2022. PMID: 35245409 Free PMC article.

8

Improved oral bioavailability of BCS class 2 compounds by self nano-emulsifying drug delivery systems (SNEDDS): the underlying mechanisms for amiodarone and talinolol.

Elgart A, Cherniakov I, Aldouby Y, Domb AJ, Hoffman A. Elgart A, et al. Pharm Res. 2013 Dec;30(12):3029-44. doi: 10.1007/s11095-013-1063-y. Epub 2013 May 18. Pharm Res. 2013. PMID: 23686373

9

Novel D-xylose derivatives stimulate muscle glucose uptake by activating AMP-activated protein kinase alpha.

Gruzman A, Shamni O, Ben Yakir M, Sandovski D, Elgart A, Alpert E, Cohen G, Hoffman A, Katzhendler Y, Cerasi E, Sasson S. Gruzman A, et al. Among authors: elgart a. J Med Chem. 2008 Dec 25;51(24):8096-108. doi: 10.1021/jm8008713. J Med Chem. 2008. PMID: 19049348

10

Polysaccharide pharmacokinetics: amphotericin B arabinogalactan conjugate-a drug delivery system or a new pharmaceutical entity?

Elgart A, Farber S, Domb AJ, Polacheck I, Hoffman A. Elgart A, et al. Biomacromolecules. 2010 Aug 9;11(8):1972-7. doi: 10.1021/bm100298r. Biomacromolecules. 2010. PMID: 20690709

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