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Dual Inhibition of Bruton's Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin's B Cell Malignancies.
Alfaro J, Pérez de Arce F, Belmar S, Fuentealba G, Avila P, Ureta G, Flores C, Acuña C, Delgado L, Gaete D, Pujala B, Barde A, Nayak AK, Upendra TVR, Patel D, Chauhan S, Sharma VK, Kanno S, Almirez RG, Hung DT, Chakravarty S, Rai R, Bernales S, Quinn KP, Pham SM, McCullagh E. Alfaro J, et al. Among authors: avila p. J Pharmacol Exp Ther. 2017 May;361(2):312-321. doi: 10.1124/jpet.116.238022. Epub 2017 Mar 15. J Pharmacol Exp Ther. 2017. PMID: 28298527
Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK and PI3Kδ.
Pujala B, Agarwal AK, Middya S, Banerjee M, Surya A, Nayak AK, Gupta A, Khare S, Guguloth R, Randive NA, Shinde BU, Thakur A, Patel DI, Raja M, Green MJ, Alfaro J, Avila P, Pérez de Arce F, Almirez RG, Kanno S, Bernales S, Hung DT, Chakravarty S, McCullagh E, Quinn KP, Rai R, Pham SM. Pujala B, et al. Among authors: avila p. ACS Med Chem Lett. 2016 Oct 28;7(12):1161-1166. doi: 10.1021/acsmedchemlett.6b00356. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994757 Free PMC article.
5-HTP inhibits eosinophilia via intracellular endothelial 5-HTRs; SNPs in 5-HTRs associate with asthmatic lung function.
Walker MT, Bloodworth JC, Kountz TS, McCarty SL, Green JE, Ferrie RP, Campbell JA, Averill SH, Beckman KB, Grammer LC, Eng C, Avila PC, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Thyne SM, Seibold MA, Burchard EG, Kumar R, Cook-Mills JM. Walker MT, et al. Among authors: avila pc. Front Allergy. 2024 May 23;5:1385168. doi: 10.3389/falgy.2024.1385168. eCollection 2024. Front Allergy. 2024. PMID: 38845678 Free PMC article.
Effectiveness of methotrexate and leflunomide as corticoid-sparing drugs in patients with polymyalgia rheumatica.
Vinicki JP, Cusa A, Domingo D, Velasco Zamora JL, Magri S, Brigante A, Schmid MM, Ávila P, Zamora N, Sorrentino L, Rodriguez AM, Linarez M, Pisoni C, Costi C, Rodriguez Gil G, Spinetto MA, Paris VU, Perrotta N, Maliandi MDR, Rillo O, Pena C, Got J, Cavallasca J, Machado Escobar M, Iturralde C, Martire MV, Tessel R, Chocobar NS, Alarcon G. Vinicki JP, et al. Among authors: avila p. Rheumatol Adv Pract. 2024 Mar 21;8(2):rkae033. doi: 10.1093/rap/rkae033. eCollection 2024. Rheumatol Adv Pract. 2024. PMID: 38560643 Free PMC article.
324 results