Powell SN - Search Results

1

Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer.

Mutter RW, Riaz N, Ng CK, Delsite R, Piscuoglio S, Edelweiss M, Martelotto LG, Sakr RA, King TA, Giri DD, Drobnjak M, Brogi E, Bindra R, Bernheim G, Lim RS, Blecua P, Desrichard A, Higginson D, Towers R, Jiang R, Lee W, Weigelt B, Reis-Filho JS, Powell SN. Mutter RW, et al. Among authors: powell sn. J Pathol. 2017 Jun;242(2):165-177. doi: 10.1002/path.4890. Epub 2017 Apr 27. J Pathol. 2017. PMID: 28299801 Free PMC article.

2

BRCA2 keeps Rad51 in line. High-fidelity homologous recombination prevents breast and ovarian cancer?

Powell SN, Willers H, Xia F. Powell SN, et al. Mol Cell. 2002 Dec;10(6):1262-3. doi: 10.1016/s1097-2765(02)00789-x. Mol Cell. 2002. PMID: 12504001 Free article.

3

Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation.

Powell SN, Kachnic LA. Powell SN, et al. Oncogene. 2003 Sep 1;22(37):5784-91. doi: 10.1038/sj.onc.1206678. Oncogene. 2003. PMID: 12947386 Review.

4

MDC1 interacts with Rad51 and facilitates homologous recombination.

Zhang J, Ma Z, Treszezamsky A, Powell SN. Zhang J, et al. Among authors: powell sn. Nat Struct Mol Biol. 2005 Oct;12(10):902-9. doi: 10.1038/nsmb991. Epub 2005 Sep 25. Nat Struct Mol Biol. 2005. PMID: 16186822

5

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA. Powell SN, et al. Anticancer Agents Med Chem. 2008 May;8(4):448-60. doi: 10.2174/187152008784220267. Anticancer Agents Med Chem. 2008. PMID: 18473729 Review.

6

Targeting the DNA damage response for cancer therapy.

Powell SN, Bindra RS. Powell SN, et al. DNA Repair (Amst). 2009 Sep 2;8(9):1153-65. doi: 10.1016/j.dnarep.2009.04.011. Epub 2009 Jun 5. DNA Repair (Amst). 2009. PMID: 19501553 Review.

7

Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies.

Willers H, Taghian AG, Luo CM, Treszezamsky A, Sgroi DC, Powell SN. Willers H, et al. Among authors: powell sn. Mol Cancer Res. 2009 Aug;7(8):1304-9. doi: 10.1158/1541-7786.MCR-09-0149. Epub 2009 Aug 11. Mol Cancer Res. 2009. PMID: 19671671 Free PMC article.

8

The role of RPA2 phosphorylation in homologous recombination in response to replication arrest.

Shi W, Feng Z, Zhang J, Gonzalez-Suarez I, Vanderwaal RP, Wu X, Powell SN, Roti Roti JL, Gonzalo S, Zhang J. Shi W, et al. Among authors: powell sn. Carcinogenesis. 2010 Jun;31(6):994-1002. doi: 10.1093/carcin/bgq035. Epub 2010 Feb 3. Carcinogenesis. 2010. PMID: 20130019 Free PMC article.

9

Enhancing radiotherapy through a greater understanding of homologous recombination.

Barker CA, Powell SN. Barker CA, et al. Among authors: powell sn. Semin Radiat Oncol. 2010 Oct;20(4):267-273.e3. doi: 10.1016/j.semradonc.2010.05.001. Semin Radiat Oncol. 2010. PMID: 20832019 Free PMC article. Review.

10

ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.

Sirbu BM, Lachmayer SJ, Wülfing V, Marten LM, Clarkson KE, Lee LW, Gheorghiu L, Zou L, Powell SN, Dahm-Daphi J, Willers H. Sirbu BM, et al. Among authors: powell sn. PLoS One. 2011;6(8):e23053. doi: 10.1371/journal.pone.0023053. Epub 2011 Aug 12. PLoS One. 2011. PMID: 21857991 Free PMC article.

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