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Cathepsin L promotes Vascular Intimal Hyperplasia after Arterial Injury.
Cai J, Zhong H, Wu J, Chen RF, Yang H, Al-Abed Y, Li Y, Li X, Jiang W, Montenegro MF, Yuan H, Billiar T, Chen AF. Cai J, et al. Mol Med. 2017 Jun;23:92-100. doi: 10.2119/molmed.2016.00222. Epub 2016 Mar 20. Mol Med. 2017. PMID: 28332696 Free PMC article.
The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE.
Rosas-Ballina M, Goldstein RS, Gallowitsch-Puerta M, Yang L, Valdés-Ferrer SI, Patel NB, Chavan S, Al-Abed Y, Yang H, Tracey KJ. Rosas-Ballina M, et al. Mol Med. 2009 Jul-Aug;15(7-8):195-202. doi: 10.2119/molmed.2009.00039. Epub 2009 Apr 27. Mol Med. 2009. PMID: 19593403 Free PMC article.
Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis.
Ju Z, Chavan SS, Antoine DJ, Dancho M, Tsaava T, Li J, Lu B, Levine YA, Stiegler A, Tamari Y, Al-Abed Y, Roth J, Tracey KJ, Yang H. Ju Z, et al. PLoS One. 2014 Aug 15;9(8):e103992. doi: 10.1371/journal.pone.0103992. eCollection 2014. PLoS One. 2014. PMID: 25127031 Free PMC article.
MD-2 is required for disulfide HMGB1-dependent TLR4 signaling.
Yang H, Wang H, Ju Z, Ragab AA, Lundbäck P, Long W, Valdes-Ferrer SI, He M, Pribis JP, Li J, Lu B, Gero D, Szabo C, Antoine DJ, Harris HE, Golenbock DT, Meng J, Roth J, Chavan SS, Andersson U, Billiar TR, Tracey KJ, Al-Abed Y. Yang H, et al. J Exp Med. 2015 Jan 12;212(1):5-14. doi: 10.1084/jem.20141318. Epub 2015 Jan 5. J Exp Med. 2015. PMID: 25559892 Free PMC article.
HMGB1-Driven Inflammation and Intimal Hyperplasia After Arterial Injury Involves Cell-Specific Actions Mediated by TLR4.
Cai J, Yuan H, Wang Q, Yang H, Al-Abed Y, Hua Z, Wang J, Chen D, Wu J, Lu B, Pribis JP, Jiang W, Yang K, Hackam DJ, Tracey KJ, Billiar TR, Chen AF. Cai J, et al. Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2579-93. doi: 10.1161/ATVBAHA.115.305789. Epub 2015 Oct 29. Arterioscler Thromb Vasc Biol. 2015. PMID: 26515416 Free PMC article.
215 results