Lee HK - Search Results

1

Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice.

Lee HK, Willi M, Wang C, Yang CM, Smith HE, Liu C, Hennighausen L. Lee HK, et al. Nucleic Acids Res. 2017 May 5;45(8):4606-4618. doi: 10.1093/nar/gkx185. Nucleic Acids Res. 2017. PMID: 28334928 Free PMC article.

2

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.

Shin HY, Wang C, Lee HK, Yoo KH, Zeng X, Kuhns T, Yang CM, Mohr T, Liu C, Hennighausen L. Shin HY, et al. Among authors: lee hk. Nat Commun. 2017 May 31;8:15464. doi: 10.1038/ncomms15464. Nat Commun. 2017. PMID: 28561021 Free PMC article.

3

Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells.

Willi M, Yoo KH, Reinisch F, Kuhns TM, Lee HK, Wang C, Hennighausen L. Willi M, et al. Among authors: lee hk. Nat Commun. 2017 Jul 17;8:16069. doi: 10.1038/ncomms16069. Nat Commun. 2017. PMID: 28714474 Free PMC article.

4

Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation.

Lee HK, Willi M, Shin HY, Liu C, Hennighausen L. Lee HK, et al. Nucleic Acids Res. 2018 Nov 16;46(20):10796-10809. doi: 10.1093/nar/gky891. Nucleic Acids Res. 2018. PMID: 30285185 Free PMC article.

5

Targeting fidelity of adenine and cytosine base editors in mouse embryos.

Lee HK, Willi M, Miller SM, Kim S, Liu C, Liu DR, Hennighausen L. Lee HK, et al. Nat Commun. 2018 Nov 15;9(1):4804. doi: 10.1038/s41467-018-07322-7. Nat Commun. 2018. PMID: 30442934 Free PMC article.

6

Simultaneous targeting of linked loci in mouse embryos using base editing.

Lee HK, Willi M, Smith HE, Miller SM, Liu DR, Liu C, Hennighausen L. Lee HK, et al. Sci Rep. 2019 Feb 7;9(1):1662. doi: 10.1038/s41598-018-33533-5. Sci Rep. 2019. PMID: 30733567 Free PMC article.

7

Cytosine base editor 4 but not adenine base editor generates off-target mutations in mouse embryos.

Lee HK, Smith HE, Liu C, Willi M, Hennighausen L. Lee HK, et al. Commun Biol. 2020 Jan 9;3(1):19. doi: 10.1038/s42003-019-0745-3. Commun Biol. 2020. PMID: 31925293 Free PMC article.

8

The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy.

Zeng X, Lee HK, Wang C, Achikeh P, Liu C, Hennighausen L. Zeng X, et al. Among authors: lee hk. Exp Mol Med. 2020 Apr;52(4):682-690. doi: 10.1038/s12276-020-0425-x. Epub 2020 Apr 22. Exp Mol Med. 2020. PMID: 32321991 Free PMC article.

9

Activation of the SARS-CoV-2 receptor Ace2 by cytokines through pan JAK-STAT enhancers.

Hennighausen L, Lee HK. Hennighausen L, et al. Among authors: lee hk. bioRxiv [Preprint]. 2020 May 11:2020.05.11.089045. doi: 10.1101/2020.05.11.089045. bioRxiv. 2020. Update in: Cell Rep. 2020 Sep 29;32(13):108199. doi: 10.1016/j.celrep.2020.108199 PMID: 32511315 Free PMC article. Updated. Preprint.

10

Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury.

Wilflingseder J, Willi M, Lee HK, Olauson H, Jankowski J, Ichimura T, Erben R, Valerius MT, Hennighausen L, Bonventre JV. Wilflingseder J, et al. Among authors: lee hk. Nat Commun. 2020 Jul 7;11(1):3383. doi: 10.1038/s41467-020-17205-5. Nat Commun. 2020. PMID: 32636391 Free PMC article.

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