Moniot S - Search Results

1

A conserved NAD⁺ binding pocket that regulates protein-protein interactions during aging.

Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJ, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA. Li J, et al. Among authors: moniot s. Science. 2017 Mar 24;355(6331):1312-1317. doi: 10.1126/science.aad8242. Science. 2017. PMID: 28336669 Free PMC article.

2

Crystal structure analysis of human Sirt2 and its ADP-ribose complex.

Moniot S, Schutkowski M, Steegborn C. Moniot S, et al. J Struct Biol. 2013 May;182(2):136-43. doi: 10.1016/j.jsb.2013.02.012. Epub 2013 Feb 26. J Struct Biol. 2013. PMID: 23454361

3

Structures, substrates, and regulators of Mammalian sirtuins - opportunities and challenges for drug development.

Moniot S, Weyand M, Steegborn C. Moniot S, et al. Front Pharmacol. 2012 Feb 9;3:16. doi: 10.3389/fphar.2012.00016. eCollection 2012. Front Pharmacol. 2012. PMID: 22363286 Free PMC article.

4

Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol.

Lakshminarasimhan M, Curth U, Moniot S, Mosalaganti S, Raunser S, Steegborn C. Lakshminarasimhan M, et al. Among authors: moniot s. Biosci Rep. 2013 May 15;33(3):e00037. doi: 10.1042/BSR20120121. Biosci Rep. 2013. PMID: 23548308 Free PMC article.

5

Crystal structure of a class III adenylyl cyclase-like ATP-binding protein from Pseudomonas aeruginosa.

Linder J, Hupfeld E, Weyand M, Steegborn C, Moniot S. Linder J, et al. Among authors: moniot s. J Struct Biol. 2020 Aug 1;211(2):107534. doi: 10.1016/j.jsb.2020.107534. Epub 2020 May 23. J Struct Biol. 2020. PMID: 32454240

6

Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate.

Kleinboelting S, Diaz A, Moniot S, van den Heuvel J, Weyand M, Levin LR, Buck J, Steegborn C. Kleinboelting S, et al. Among authors: moniot s. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3727-32. doi: 10.1073/pnas.1322778111. Epub 2014 Feb 24. Proc Natl Acad Sci U S A. 2014. PMID: 24567411 Free PMC article.

7

A blue light receptor that mediates RNA binding and translational regulation.

Weber AM, Kaiser J, Ziegler T, Pilsl S, Renzl C, Sixt L, Pietruschka G, Moniot S, Kakoti A, Juraschitz M, Schrottke S, Lledo Bryant L, Steegborn C, Bittl R, Mayer G, Möglich A. Weber AM, et al. Among authors: moniot s. Nat Chem Biol. 2019 Nov;15(11):1085-1092. doi: 10.1038/s41589-019-0346-y. Epub 2019 Aug 26. Nat Chem Biol. 2019. PMID: 31451761 Free PMC article.

8

Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket.

Sundriyal S, Moniot S, Mahmud Z, Yao S, Di Fruscia P, Reynolds CR, Dexter DT, Sternberg MJ, Lam EW, Steegborn C, Fuchter MJ. Sundriyal S, et al. Among authors: moniot s. J Med Chem. 2017 Mar 9;60(5):1928-1945. doi: 10.1021/acs.jmedchem.6b01690. Epub 2017 Feb 15. J Med Chem. 2017. PMID: 28135086 Free PMC article.

9

Effects of 3-Bromo-4,5-dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase-1 Expression.

Pinto A, El Ali Z, Moniot S, Tamborini L, Steegborn C, Foresti R, De Micheli C. Pinto A, et al. Among authors: moniot s. ChemistryOpen. 2018 Oct 12;7(11):858-864. doi: 10.1002/open.201800185. eCollection 2018 Nov. ChemistryOpen. 2018. PMID: 30397576 Free PMC article.

10

Development of 1,2,4-Oxadiazoles as Potent and Selective Inhibitors of the Human Deacetylase Sirtuin 2: Structure-Activity Relationship, X-ray Crystal Structure, and Anticancer Activity.

Moniot S, Forgione M, Lucidi A, Hailu GS, Nebbioso A, Carafa V, Baratta F, Altucci L, Giacché N, Passeri D, Pellicciari R, Mai A, Steegborn C, Rotili D. Moniot S, et al. J Med Chem. 2017 Mar 23;60(6):2344-2360. doi: 10.1021/acs.jmedchem.6b01609. Epub 2017 Mar 14. J Med Chem. 2017. PMID: 28240897

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