Harris DL - Search Results

1

Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?

Li F, Ling X, Harris DL, Liao J, Wang Y, Westover D, Jiang G, Xu B, Boland PM, Jin C. Li F, et al. Among authors: harris dl. Am J Cancer Res. 2017 Feb 1;7(2):370-382. eCollection 2017. Am J Cancer Res. 2017. PMID: 28337384 Free PMC article.

2

Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies.

Jin C, Decker AM, Harris DL, Blough BE. Jin C, et al. Among authors: harris dl. ACS Chem Neurosci. 2016 Oct 19;7(10):1418-1432. doi: 10.1021/acschemneuro.6b00182. Epub 2016 Aug 16. ACS Chem Neurosci. 2016. PMID: 27499251 Free PMC article.

3

Design, Synthesis, and Structure-Activity Relationship Studies of Novel GPR88 Agonists (4-Substituted-phenyl)acetamides Based on the Reversed Amide Scaffold.

Rahman MT, Guan D, Chaminda Lakmal HH, Decker AM, Imler GH, Kerr AT, Harris DL, Jin C. Rahman MT, et al. Among authors: harris dl. ACS Chem Neurosci. 2024 Jan 3;15(1):169-192. doi: 10.1021/acschemneuro.3c00684. Epub 2023 Dec 12. ACS Chem Neurosci. 2024. PMID: 38086012 Free PMC article.

4

Discovery of Novel Proline-Based Neuropeptide FF Receptor Antagonists.

Nguyen T, Decker AM, Langston TL, Mathews KM, Siemian JN, Li JX, Harris DL, Runyon SP, Zhang Y. Nguyen T, et al. Among authors: harris dl. ACS Chem Neurosci. 2017 Oct 18;8(10):2290-2308. doi: 10.1021/acschemneuro.7b00219. Epub 2017 Aug 9. ACS Chem Neurosci. 2017. PMID: 28737888 Free PMC article.

5

Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.

Amato GS, Manke A, Harris DL, Wiethe RW, Vasukuttan V, Snyder RW, Lefever TW, Cortes R, Zhang Y, Wang S, Runyon SP, Maitra R. Amato GS, et al. Among authors: harris dl. J Med Chem. 2018 May 24;61(10):4370-4385. doi: 10.1021/acs.jmedchem.7b01820. Epub 2018 May 10. J Med Chem. 2018. PMID: 29688015 Free PMC article.

6

Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.

Narayanan S, Harris DL, Maitra R, Runyon SP. Narayanan S, et al. Among authors: harris dl. J Med Chem. 2015 Oct 22;58(20):7913-27. doi: 10.1021/acs.jmedchem.5b00527. Epub 2015 Jul 10. J Med Chem. 2015. PMID: 26102594 Free PMC article. Review.

7

Structure-Activity Relationship Development Efforts towards Peripherally Selective Analogs of the Cannabinoid Receptor Partial Agonist BAY 59-3074.

Amato G, Vasukuttan V, Harris D, Laudermilk L, Lucitti J, Runyon S, Maitra R. Amato G, et al. Molecules. 2022 Sep 2;27(17):5672. doi: 10.3390/molecules27175672. Molecules. 2022. PMID: 36080443 Free PMC article.

8

The development of diphenyleneiodonium analogs as GPR3 agonists.

Gay EA, Harris DL, Wilson JW, Blough BE. Gay EA, et al. Among authors: harris dl. Bioorg Med Chem Lett. 2023 Oct 1;94:129427. doi: 10.1016/j.bmcl.2023.129427. Epub 2023 Aug 2. Bioorg Med Chem Lett. 2023. PMID: 37541631 Free PMC article.

9

Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor.

Perrey DA, German NA, Decker AM, Thorn D, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Perrey DA, et al. Among authors: harris dl. ACS Chem Neurosci. 2015 Apr 15;6(4):599-614. doi: 10.1021/cn500330v. Epub 2015 Feb 12. ACS Chem Neurosci. 2015. PMID: 25643283 Free PMC article.

10

The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.

Perrey DA, Decker AM, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Perrey DA, et al. Among authors: harris dl. Bioorg Med Chem. 2015 Sep 1;23(17):5709-24. doi: 10.1016/j.bmc.2015.07.013. Epub 2015 Jul 16. Bioorg Med Chem. 2015. PMID: 26216017 Free PMC article.

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