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A chemical chaperone improves muscle function in mice with a RyR1 mutation.
Lee CS, Hanna AD, Wang H, Dagnino-Acosta A, Joshi AD, Knoblauch M, Xia Y, Georgiou DK, Xu J, Long C, Amano H, Reynolds C, Dong K, Martin JC, Lagor WR, Rodney GG, Sahin E, Sewry C, Hamilton SL. Lee CS, et al. Among authors: rodney gg. Nat Commun. 2017 Mar 24;8:14659. doi: 10.1038/ncomms14659. Nat Commun. 2017. PMID: 28337975 Free PMC article.
Regulation of RYR1 activity by Ca(2+) and calmodulin.
Rodney GG, Williams BY, Strasburg GM, Beckingham K, Hamilton SL. Rodney GG, et al. Biochemistry. 2000 Jul 4;39(26):7807-12. doi: 10.1021/bi0005660. Biochemistry. 2000. PMID: 10869186
Determinants for calmodulin binding on voltage-dependent Ca2+ channels.
Pate P, Mochca-Morales J, Wu Y, Zhang JZ, Rodney GG, Serysheva II, Williams BY, Anderson ME, Hamilton SL. Pate P, et al. Among authors: rodney gg. J Biol Chem. 2000 Dec 15;275(50):39786-92. doi: 10.1074/jbc.M007158200. J Biol Chem. 2000. PMID: 11005820 Free article.
Lobe-dependent regulation of ryanodine receptor type 1 by calmodulin.
Xiong LW, Newman RA, Rodney GG, Thomas O, Zhang JZ, Persechini A, Shea MA, Hamilton SL. Xiong LW, et al. Among authors: rodney gg. J Biol Chem. 2002 Oct 25;277(43):40862-70. doi: 10.1074/jbc.M206763200. Epub 2002 Aug 15. J Biol Chem. 2002. PMID: 12185083 Free article.
AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.
Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. Lanner JT, et al. Among authors: rodney gg. Nat Med. 2012 Jan 8;18(2):244-51. doi: 10.1038/nm.2598. Nat Med. 2012. PMID: 22231556 Free PMC article.
66 results