Baumann U - Search Results

1

Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.

Halekotte J, Witt L, Ianes C, Krüger M, Bührmann M, Rauh D, Pichlo C, Brunstein E, Luxenburger A, Baumann U, Knippschild U, Bischof J, Peifer C. Halekotte J, et al. Among authors: baumann u. Molecules. 2017 Mar 24;22(4):522. doi: 10.3390/molecules22040522. Molecules. 2017. PMID: 28338621 Free PMC article.

2

The structure of Aquifex aeolicus FtsH in the ADP-bound state reveals a C2-symmetric hexamer.

Vostrukhina M, Popov A, Brunstein E, Lanz MA, Baumgartner R, Bieniossek C, Schacherl M, Baumann U. Vostrukhina M, et al. Among authors: baumann u. Acta Crystallogr D Biol Crystallogr. 2015 Jun;71(Pt 6):1307-18. doi: 10.1107/S1399004715005945. Epub 2015 May 14. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26057670

3

Structural Basis of Proline-Proline Peptide Bond Specificity of the Metalloprotease Zmp1 Implicated in Motility of Clostridium difficile.

Schacherl M, Pichlo C, Neundorf I, Baumann U. Schacherl M, et al. Among authors: baumann u. Structure. 2015 Sep 1;23(9):1632-1642. doi: 10.1016/j.str.2015.06.018. Epub 2015 Jul 23. Structure. 2015. PMID: 26211609 Free article.

4

The first crystal structure of the peptidase domain of the U32 peptidase family.

Schacherl M, Montada AA, Brunstein E, Baumann U. Schacherl M, et al. Among authors: baumann u. Acta Crystallogr D Biol Crystallogr. 2015 Dec 1;71(Pt 12):2505-12. doi: 10.1107/S1399004715019549. Epub 2015 Nov 27. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26627657

5

Production, Crystallization and Structure Determination of C. difficile PPEP-1 via Microseeding and Zinc-SAD.

Pichlo C, Montada AA, Schacherl M, Baumann U. Pichlo C, et al. Among authors: baumann u. J Vis Exp. 2016 Dec 30;(118):55022. doi: 10.3791/55022. J Vis Exp. 2016. PMID: 28060332 Free PMC article.

6

A CK1 FRET biosensor reveals that DDX3X is an essential activator of CK1ε.

Dolde C, Bischof J, Grüter S, Montada A, Halekotte J, Peifer C, Kalbacher H, Baumann U, Knippschild U, Suter B. Dolde C, et al. Among authors: baumann u. J Cell Sci. 2018 Jan 4;131(1):jcs207316. doi: 10.1242/jcs.207316. J Cell Sci. 2018. PMID: 29222110 Free PMC article.

7

A family of unconventional deubiquitinases with modular chain specificity determinants.

Hermanns T, Pichlo C, Woiwode I, Klopffleisch K, Witting KF, Ovaa H, Baumann U, Hofmann K. Hermanns T, et al. Among authors: baumann u. Nat Commun. 2018 Feb 23;9(1):799. doi: 10.1038/s41467-018-03148-5. Nat Commun. 2018. PMID: 29476094 Free PMC article.

8

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.

García-Reyes B, Witt L, Jansen B, Karasu E, Gehring T, Leban J, Henne-Bruns D, Pichlo C, Brunstein E, Baumann U, Wesseler F, Rathmer B, Schade D, Peifer C, Knippschild U. García-Reyes B, et al. Among authors: baumann u. J Med Chem. 2018 May 10;61(9):4087-4102. doi: 10.1021/acs.jmedchem.8b00095. Epub 2018 May 1. J Med Chem. 2018. PMID: 29630366

9

Heterologous expression and characterization of a novel serine protease from Daphnia magna: A possible role in susceptibility to toxic cyanobacteria.

Lange J, Demir F, Huesgen PF, Baumann U, von Elert E, Pichlo C. Lange J, et al. Among authors: baumann u. Aquat Toxicol. 2018 Dec;205:140-147. doi: 10.1016/j.aquatox.2018.09.013. Epub 2018 Sep 26. Aquat Toxicol. 2018. PMID: 30384195

10

Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.

Luxenburger A, Schmidt D, Ianes C, Pichlo C, Krüger M, von Drathen T, Brunstein E, Gainsford GJ, Baumann U, Knippschild U, Peifer C. Luxenburger A, et al. Among authors: baumann u. Molecules. 2019 Mar 1;24(5):873. doi: 10.3390/molecules24050873. Molecules. 2019. PMID: 30832206 Free PMC article.

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