Ward SA - Search Results

1

Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration.

Aljayyoussi G, Jenkins VA, Sharma R, Ardrey A, Donnellan S, Ward SA, Biagini GA. Aljayyoussi G, et al. Among authors: ward sa. Sci Rep. 2017 Mar 29;7(1):502. doi: 10.1038/s41598-017-00529-6. Sci Rep. 2017. PMID: 28356552 Free PMC article.

2

The digestive food vacuole of the malaria parasite is a dynamic intracellular Ca2+ store.

Biagini GA, Bray PG, Spiller DG, White MR, Ward SA. Biagini GA, et al. Among authors: ward sa. J Biol Chem. 2003 Jul 25;278(30):27910-5. doi: 10.1074/jbc.M304193200. Epub 2003 May 8. J Biol Chem. 2003. PMID: 12740366 Free article.

3

Heme binding contributes to antimalarial activity of bis-quaternary ammoniums.

Biagini GA, Richier E, Bray PG, Calas M, Vial H, Ward SA. Biagini GA, et al. Among authors: ward sa. Antimicrob Agents Chemother. 2003 Aug;47(8):2584-9. doi: 10.1128/AAC.47.8.2584-2589.2003. Antimicrob Agents Chemother. 2003. PMID: 12878523 Free PMC article.

4

Antimalarial chemotherapy: young guns or back to the future?

Biagini GA, O'Neill PM, Nzila A, Ward SA, Bray PG. Biagini GA, et al. Among authors: ward sa. Trends Parasitol. 2003 Nov;19(11):479-87. doi: 10.1016/j.pt.2003.09.011. Trends Parasitol. 2003. PMID: 14580958 Review. No abstract available.

5

Characterization of the choline carrier of Plasmodium falciparum: a route for the selective delivery of novel antimalarial drugs.

Biagini GA, Pasini EM, Hughes R, De Koning HP, Vial HJ, O'Neill PM, Ward SA, Bray PG. Biagini GA, et al. Among authors: ward sa. Blood. 2004 Nov 15;104(10):3372-7. doi: 10.1182/blood-2004-03-1084. Epub 2004 Jun 17. Blood. 2004. PMID: 15205262 Free article.

6

Malaria parasite transporters as a drug-delivery strategy.

Biagini GA, Ward SA, Bray PG. Biagini GA, et al. Among authors: ward sa. Trends Parasitol. 2005 Jul;21(7):299-301. doi: 10.1016/j.pt.2005.05.013. Trends Parasitol. 2005. PMID: 15923144 Review.

7

Current drug development portfolio for antimalarial therapies.

Biagini GA, O'Neill PM, Bray PG, Ward SA. Biagini GA, et al. Among authors: ward sa. Curr Opin Pharmacol. 2005 Oct;5(5):473-8. doi: 10.1016/j.coph.2005.05.004. Curr Opin Pharmacol. 2005. PMID: 16084770 Review.

8

Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+.

Biagini GA, Fidock DA, Bray PG, Ward SA. Biagini GA, et al. Among authors: ward sa. Antimicrob Agents Chemother. 2005 Nov;49(11):4807-8. doi: 10.1128/AAC.49.11.4807-4808.2005. Antimicrob Agents Chemother. 2005. PMID: 16251339 Free PMC article. No abstract available.

9

Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria.

Biagini GA, Viriyavejakul P, O'neill PM, Bray PG, Ward SA. Biagini GA, et al. Among authors: ward sa. Antimicrob Agents Chemother. 2006 May;50(5):1841-51. doi: 10.1128/AAC.50.5.1841-1851.2006. Antimicrob Agents Chemother. 2006. PMID: 16641458 Free PMC article.

10

A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.

O'Neill PM, Ward SA, Berry NG, Jeyadevan JP, Biagini GA, Asadollaly E, Park BK, Bray PG. O'Neill PM, et al. Among authors: ward sa. Curr Top Med Chem. 2006;6(5):479-507. doi: 10.2174/156802606776743147. Curr Top Med Chem. 2006. PMID: 16719804 Review.

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