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Page 1
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain.
Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P. Ng KP, et al. Among authors: comley ra. Alzheimers Res Ther. 2017 Mar 31;9(1):25. doi: 10.1186/s13195-017-0253-y. Alzheimers Res Ther. 2017. PMID: 28359327 Free PMC article.
[18F]BTK-1: A Novel Positron Emission Tomography Tracer for Imaging Bruton's Tyrosine Kinase.
Skaddan MB, Wooten DW, Wilcox KC, Voorbach MJ, Reuter DR, Jia ZJ, Foster-Duke KD, Hickson JA, Vaidyanathan S, Reed AD, Tovcimak AE, Guo Q, Comley RA, Lee L, Finnema SJ, Mudd SR. Skaddan MB, et al. Among authors: comley ra. Mol Imaging Biol. 2022 Oct;24(5):830-841. doi: 10.1007/s11307-022-01733-1. Epub 2022 Apr 28. Mol Imaging Biol. 2022. PMID: 35482146
Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography.
Comley RA, Salinas CA, Slifstein M, Petrone M, Marzano C, Bennacef I, Shotbolt P, Van der Aart J, Neve M, Iavarone L, Gomeni R, Laruelle M, Gray FA, Gunn RN, Rabiner EA. Comley RA, et al. J Pharmacol Exp Ther. 2013 Aug;346(2):311-7. doi: 10.1124/jpet.112.202895. Epub 2013 May 17. J Pharmacol Exp Ther. 2013. PMID: 23685546 Clinical Trial.
Human Kinetic Modeling of the 5HT6 PET Radioligand 11C-GSK215083 and Its Utility for Determining Occupancy at Both 5HT6 and 5HT2A Receptors by SB742457 as a Potential Therapeutic Mechanism of Action in Alzheimer Disease.
Parker CA, Rabiner EA, Gunn RN, Searle G, Martarello L, Comley RA, Davy M, Wilson AA, Houle S, Mizrahi R, Laruelle M, Cunningham VJ. Parker CA, et al. Among authors: comley ra. J Nucl Med. 2015 Dec;56(12):1901-9. doi: 10.2967/jnumed.115.162743. Epub 2015 Sep 17. J Nucl Med. 2015. PMID: 26383152 Free article.
Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline.
Sturm S, Forsberg A, Nave S, Stenkrona P, Seneca N, Varrone A, Comley RA, Fazio P, Jamois C, Nakao R, Ejduk Z, Al-Tawil N, Akenine U, Halldin C, Andreasen N, Ricci B. Sturm S, et al. Among authors: comley ra. Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):382-391. doi: 10.1007/s00259-016-3510-6. Epub 2016 Sep 16. Eur J Nucl Med Mol Imaging. 2017. PMID: 27633250 Free PMC article. Clinical Trial.
Characterization of 3 Novel Tau Radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in Healthy Controls and in Alzheimer Subjects.
Wong DF, Comley RA, Kuwabara H, Rosenberg PB, Resnick SM, Ostrowitzki S, Vozzi C, Boess F, Oh E, Lyketsos CG, Honer M, Gobbi L, Klein G, George N, Gapasin L, Kitzmiller K, Roberts J, Sevigny J, Nandi A, Brasic J, Mishra C, Thambisetty M, Mogekar A, Mathur A, Albert M, Dannals RF, Borroni E. Wong DF, et al. Among authors: comley ra. J Nucl Med. 2018 Dec;59(12):1869-1876. doi: 10.2967/jnumed.118.209916. Epub 2018 May 4. J Nucl Med. 2018. PMID: 29728519 Free PMC article.
A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18F-MK-6240 PET.
Seibyl JP, DuBois JM, Racine A, Collins J, Guo Q, Wooten D, Stage E, Cheng D, Gunn RN, Porat L, Whittington A, Kuo PH, Ichise M, Comley R, Martarello L, Salinas C. Seibyl JP, et al. J Nucl Med. 2023 Mar;64(3):444-451. doi: 10.2967/jnumed.122.264371. Epub 2022 Sep 29. J Nucl Med. 2023. PMID: 36175137 Free PMC article.
38 results