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Carrier priming with CRM 197 or diphtheria toxoid has a different impact on the immunogenicity of the respective glycoconjugates: biophysical and immunochemical interpretation.
Pecetta S, Lo Surdo P, Tontini M, Proietti D, Zambonelli C, Bottomley MJ, Biagini M, Berti F, Costantino P, Romano MR; Study Group. Pecetta S, et al. Among authors: tontini m. Vaccine. 2015 Jan 3;33(2):314-20. doi: 10.1016/j.vaccine.2014.11.026. Epub 2014 Nov 22. Vaccine. 2015. PMID: 25448110
Carrier priming effect of CRM197 is related to an enhanced B and T cell activation in meningococcal serogroup A conjugate vaccination. Immunological comparison between CRM197 and diphtheria toxoid.
Pecetta S, Tontini M, Faenzi E, Cioncada R, Proietti D, Seubert A, Nuti S, Berti F, Romano MR. Pecetta S, et al. Among authors: tontini m. Vaccine. 2016 Apr 29;34(20):2334-41. doi: 10.1016/j.vaccine.2016.03.055. Epub 2016 Mar 23. Vaccine. 2016. PMID: 27015733
Preclinical studies on new proteins as carrier for glycoconjugate vaccines.
Tontini M, Romano MR, Proietti D, Balducci E, Micoli F, Balocchi C, Santini L, Masignani V, Berti F, Costantino P. Tontini M, et al. Vaccine. 2016 Jul 29;34(35):4235-4242. doi: 10.1016/j.vaccine.2016.06.039. Epub 2016 Jun 24. Vaccine. 2016. PMID: 27317455 Free article.
Beta-glucan-CRM197 conjugates as candidates antifungal vaccines.
Bromuro C, Romano M, Chiani P, Berti F, Tontini M, Proietti D, Mori E, Torosantucci A, Costantino P, Rappuoli R, Cassone A. Bromuro C, et al. Among authors: tontini m. Vaccine. 2010 Mar 19;28(14):2615-23. doi: 10.1016/j.vaccine.2010.01.012. Epub 2010 Jan 21. Vaccine. 2010. PMID: 20096763
Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X.
Micoli F, Romano MR, Tontini M, Cappelletti E, Gavini M, Proietti D, Rondini S, Swennen E, Santini L, Filippini S, Balocchi C, Adamo R, Pluschke G, Norheim G, Pollard A, Saul A, Rappuoli R, MacLennan CA, Berti F, Costantino P. Micoli F, et al. Among authors: tontini m. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19077-82. doi: 10.1073/pnas.1314476110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191022 Free PMC article.
Investigating the immunodominance of carbohydrate antigens in a bivalent unimolecular glycoconjugate vaccine against serogroup A and C meningococcal disease.
Adamo R, Nilo A, Harfouche C, Brogioni B, Pecetta S, Brogioni G, Balducci E, Pinto V, Filippini S, Mori E, Tontini M, Romano MR, Costantino P, Berti F. Adamo R, et al. Among authors: tontini m. Glycoconj J. 2014 Dec;31(9):637-47. doi: 10.1007/s10719-014-9559-1. Epub 2014 Sep 26. Glycoconj J. 2014. PMID: 25256065
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