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Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner.
Mishra VK, Wegwitz F, Kosinsky RL, Sen M, Baumgartner R, Wulff T, Siveke JT, Schildhaus HU, Najafova Z, Kari V, Kohlhof H, Hessmann E, Johnsen SA. Mishra VK, et al. Among authors: baumgartner r. Nucleic Acids Res. 2017 Jun 20;45(11):6334-6349. doi: 10.1093/nar/gkx212. Nucleic Acids Res. 2017. PMID: 28369619 Free PMC article.
Proteasome inhibition by peptide-semicarbazones.
Leban J, Blisse M, Krauss B, Rath S, Baumgartner R, Seifert MH. Leban J, et al. Among authors: baumgartner r. Bioorg Med Chem. 2008 Apr 15;16(8):4579-88. doi: 10.1016/j.bmc.2008.02.042. Epub 2008 Feb 15. Bioorg Med Chem. 2008. PMID: 18313310
A novel TLR7 agonist reverses NK cell anergy and cures RMA-S lymphoma-bearing mice.
Wiedemann GM, Jacobi SJ, Chaloupka M, Krächan A, Hamm S, Strobl S, Baumgartner R, Rothenfusser S, Duewell P, Endres S, Kobold S. Wiedemann GM, et al. Among authors: baumgartner r. Oncoimmunology. 2016 May 31;5(7):e1189051. doi: 10.1080/2162402X.2016.1189051. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622045 Free PMC article.
Thienopyrimidines as β3-adrenoceptor agonists: hit-to-lead optimization.
Tasler S, Baumgartner R, Ammendola A, Schachtner J, Wieber T, Blisse M, Rath S, Zaja M, Klahn P, Quotschalla U, Ney P. Tasler S, et al. Among authors: baumgartner r. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6108-15. doi: 10.1016/j.bmcl.2010.08.039. Epub 2010 Aug 12. Bioorg Med Chem Lett. 2010. PMID: 20833036
Dual binding mode of a novel series of DHODH inhibitors.
Baumgartner R, Walloschek M, Kralik M, Gotschlich A, Tasler S, Mies J, Leban J. Baumgartner R, et al. J Med Chem. 2006 Feb 23;49(4):1239-47. doi: 10.1021/jm0506975. J Med Chem. 2006. PMID: 16480261
A vHTS approach for the identification of beta-adrenoceptor ligands.
Tasler S, Baumgartner R, Aschenbrenner A, Ammendola A, Wolf K, Wieber T, Schachtner J, Blisse M, Quotschalla U, Ney P. Tasler S, et al. Among authors: baumgartner r. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3399-404. doi: 10.1016/j.bmcl.2010.04.009. Epub 2010 Apr 9. Bioorg Med Chem Lett. 2010. PMID: 20434333
1,012 results