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A novel approach for integrative studies on neurodegenerative diseases in human brains.
Theofilas P, Polichiso L, Wang X, Lima LC, Alho ATL, Leite REP, Suemoto CK, Pasqualucci CA, Jacob-Filho W, Heinsen H; Brazilian Aging Brain Study Group; Grinberg LT. Theofilas P, et al. J Neurosci Methods. 2014 Apr 15;226:171-183. doi: 10.1016/j.jneumeth.2014.01.030. Epub 2014 Feb 3. J Neurosci Methods. 2014. PMID: 24503023 Free PMC article.
Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.
Theofilas P, Ehrenberg AJ, Nguy A, Thackrey JM, Dunlop S, Mejia MB, Alho AT, Paraizo Leite RE, Rodriguez RD, Suemoto CK, Nascimento CF, Chin M, Medina-Cleghorn D, Cuervo AM, Arkin M, Seeley WW, Miller BL, Nitrini R, Pasqualucci CA, Filho WJ, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Theofilas P, et al. Neurobiol Aging. 2018 Jan;61:1-12. doi: 10.1016/j.neurobiolaging.2017.09.007. Epub 2017 Sep 20. Neurobiol Aging. 2018. PMID: 29031088 Free PMC article.
Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery.
Theofilas P, Ehrenberg AJ, Dunlop S, Di Lorenzo Alho AT, Nguy A, Leite REP, Rodriguez RD, Mejia MB, Suemoto CK, Ferretti-Rebustini REL, Polichiso L, Nascimento CF, Seeley WW, Nitrini R, Pasqualucci CA, Jacob Filho W, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Theofilas P, et al. Alzheimers Dement. 2017 Mar;13(3):236-246. doi: 10.1016/j.jalz.2016.06.2362. Epub 2016 Aug 8. Alzheimers Dement. 2017. PMID: 27513978 Free PMC article.
Selective Vulnerability of Brainstem Nuclei in Distinct Tauopathies: A Postmortem Study.
Eser RA, Ehrenberg AJ, Petersen C, Dunlop S, Mejia MB, Suemoto CK, Walsh CM, Rajana H, Oh J, Theofilas P, Seeley WW, Miller BL, Neylan TC, Heinsen H, Grinberg LT. Eser RA, et al. Among authors: theofilas p. J Neuropathol Exp Neurol. 2018 Feb 1;77(2):149-161. doi: 10.1093/jnen/nlx113. J Neuropathol Exp Neurol. 2018. PMID: 29304218 Free PMC article.
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.
Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW. Grinberg LT, et al. Among authors: theofilas p. Acta Neuropathol. 2013 Apr;125(4):581-93. doi: 10.1007/s00401-013-1080-2. Epub 2013 Jan 31. Acta Neuropathol. 2013. PMID: 23371364 Free PMC article.
Profound degeneration of wake-promoting neurons in Alzheimer's disease.
Oh J, Eser RA, Ehrenberg AJ, Morales D, Petersen C, Kudlacek J, Dunlop SR, Theofilas P, Resende EDPF, Cosme C, Alho EJL, Spina S, Walsh CM, Miller BL, Seeley WW, Bittencourt JC, Neylan TC, Heinsen H, Grinberg LT. Oh J, et al. Among authors: theofilas p. Alzheimers Dement. 2019 Oct;15(10):1253-1263. doi: 10.1016/j.jalz.2019.06.3916. Epub 2019 Aug 12. Alzheimers Dement. 2019. PMID: 31416793 Free PMC article.
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