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Page 1
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD. Anderson KA, et al. Among authors: grimsrud pa. Cell Metab. 2017 Apr 4;25(4):838-855.e15. doi: 10.1016/j.cmet.2017.03.003. Cell Metab. 2017. PMID: 28380376 Free PMC article.
Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction.
Curtis JM, Grimsrud PA, Wright WS, Xu X, Foncea RE, Graham DW, Brestoff JR, Wiczer BM, Ilkayeva O, Cianflone K, Muoio DE, Arriaga EA, Bernlohr DA. Curtis JM, et al. Among authors: grimsrud pa. Diabetes. 2010 May;59(5):1132-42. doi: 10.2337/db09-1105. Epub 2010 Feb 11. Diabetes. 2010. PMID: 20150287 Free PMC article.
Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy model.
Martin AS, Abraham DM, Hershberger KA, Bhatt DP, Mao L, Cui H, Liu J, Liu X, Muehlbauer MJ, Grimsrud PA, Locasale JW, Payne RM, Hirschey MD. Martin AS, et al. Among authors: grimsrud pa. JCI Insight. 2017 Jul 20;2(14):e93885. doi: 10.1172/jci.insight.93885. eCollection 2017 Jul 20. JCI Insight. 2017. PMID: 28724806 Free PMC article.
The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.
White PJ, McGarrah RW, Grimsrud PA, Tso SC, Yang WH, Haldeman JM, Grenier-Larouche T, An J, Lapworth AL, Astapova I, Hannou SA, George T, Arlotto M, Olson LB, Lai M, Zhang GF, Ilkayeva O, Herman MA, Wynn RM, Chuang DT, Newgard CB. White PJ, et al. Among authors: grimsrud pa. Cell Metab. 2018 Jun 5;27(6):1281-1293.e7. doi: 10.1016/j.cmet.2018.04.015. Epub 2018 May 17. Cell Metab. 2018. PMID: 29779826 Free PMC article.
Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.
Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM. Fisher-Wellman KH, et al. Among authors: grimsrud pa. Cell Rep. 2019 Feb 5;26(6):1557-1572.e8. doi: 10.1016/j.celrep.2019.01.057. Cell Rep. 2019. PMID: 30726738 Free PMC article.
38 results