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Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-β1/ EMT genes for activation or repression.
Pezone A, Taddei ML, Tramontano A, Dolcini J, Boffo FL, De Rosa M, Parri M, Stinziani S, Comito G, Porcellini A, Raugei G, Gackowski D, Zarakowska E, Olinski R, Gabrielli A, Chiarugi P, Avvedimento EV. Pezone A, et al. Among authors: tramontano a. Nucleic Acids Res. 2020 Sep 18;48(16):8943-8958. doi: 10.1093/nar/gkaa599. Nucleic Acids Res. 2020. PMID: 32697292 Free PMC article.
LSD1: more than demethylation of histone lysine residues.
Perillo B, Tramontano A, Pezone A, Migliaccio A. Perillo B, et al. Among authors: tramontano a. Exp Mol Med. 2020 Dec;52(12):1936-1947. doi: 10.1038/s12276-020-00542-2. Epub 2020 Dec 14. Exp Mol Med. 2020. PMID: 33318631 Free PMC article. Review.
Tracing and tracking epiallele families in complex DNA populations.
Pezone A, Tramontano A, Scala G, Cuomo M, Riccio P, De Nicola S, Porcellini A, Chiariotti L, Avvedimento EV. Pezone A, et al. Among authors: tramontano a. NAR Genom Bioinform. 2020 Nov 16;2(4):lqaa096. doi: 10.1093/nargab/lqaa096. eCollection 2020 Dec. NAR Genom Bioinform. 2020. PMID: 33575640 Free PMC article.
Loss of p53 activates thyroid hormone via type 2 deiodinase and enhances DNA damage.
Nappi A, Miro C, Pezone A, Tramontano A, Di Cicco E, Sagliocchi S, Cicatiello AG, Murolo M, Torabinejad S, Abbotto E, Caiazzo G, Raia M, Stornaiuolo M, Antonini D, Fabbrocini G, Salvatore D, Avvedimento VE, Dentice M. Nappi A, et al. Among authors: tramontano a. Nat Commun. 2023 Mar 4;14(1):1244. doi: 10.1038/s41467-023-36755-y. Nat Commun. 2023. PMID: 36871014 Free PMC article.
393 results