Verdegaal EME - Search Results

1

IDO and galectin-3 hamper the ex vivo generation of clinical grade tumor-specific T cells for adoptive cell therapy in metastatic melanoma.

Melief SM, Visser M, van der Burg SH, Verdegaal EME. Melief SM, et al. Among authors: verdegaal eme. Cancer Immunol Immunother. 2017 Jul;66(7):913-926. doi: 10.1007/s00262-017-1995-x. Epub 2017 Apr 11. Cancer Immunol Immunother. 2017. PMID: 28401257 Free PMC article.

2

Successful treatment of metastatic melanoma by adoptive transfer of blood-derived polyclonal tumor-specific CD4+ and CD8+ T cells in combination with low-dose interferon-alpha.

Verdegaal EM, Visser M, Ramwadhdoebé TH, van der Minne CE, van Steijn JA, Kapiteijn E, Haanen JB, van der Burg SH, Nortier JW, Osanto S. Verdegaal EM, et al. Cancer Immunol Immunother. 2011 Jul;60(7):953-63. doi: 10.1007/s00262-011-1004-8. Epub 2011 Mar 24. Cancer Immunol Immunother. 2011. PMID: 21431917 Free PMC article. Clinical Trial.

3

The development of standard samples with a defined number of antigen-specific T cells to harmonize T cell assays: a proof-of-principle study.

Singh SK, Tummers B, Schumacher TN, Gomez R, Franken KL, Verdegaal EM, Laske K, Gouttefangeas C, Ottensmeier C, Welters MJ, Britten CM, van der Burg SH. Singh SK, et al. Cancer Immunol Immunother. 2013 Mar;62(3):489-501. doi: 10.1007/s00262-012-1351-0. Epub 2012 Sep 18. Cancer Immunol Immunother. 2013. PMID: 22986454 Free PMC article.

4

Inhibition of the type I immune responses of human monocytes by IFN-α and IFN-β.

de Paus RA, van Wengen A, Schmidt I, Visser M, Verdegaal EM, van Dissel JT, van de Vosse E. de Paus RA, et al. Cytokine. 2013 Feb;61(2):645-55. doi: 10.1016/j.cyto.2012.12.005. Epub 2013 Jan 5. Cytokine. 2013. PMID: 23299081

5

Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma.

Gao L, Smit MA, van den Oord JJ, Goeman JJ, Verdegaal EM, van der Burg SH, Stas M, Beck S, Gruis NA, Tensen CP, Willemze R, Peeper DS, van Doorn R. Gao L, et al. Pigment Cell Melanoma Res. 2013 Jul;26(4):542-54. doi: 10.1111/pcmr.12096. Epub 2013 Apr 17. Pigment Cell Melanoma Res. 2013. PMID: 23590314

6

Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma.

Kaplon J, Hömig-Hölzel C, Gao L, Meissl K, Verdegaal EM, van der Burg SH, van Doorn R, Peeper DS. Kaplon J, et al. Pigment Cell Melanoma Res. 2014 Jul;27(4):640-52. doi: 10.1111/pcmr.12248. Epub 2014 May 14. Pigment Cell Melanoma Res. 2014. PMID: 24703243

7

Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?

Svane IM, Verdegaal EM. Svane IM, et al. Cancer Immunol Immunother. 2014 Oct;63(10):1081-91. doi: 10.1007/s00262-014-1580-5. Epub 2014 Aug 7. Cancer Immunol Immunother. 2014. PMID: 25099366 Free PMC article. Review.

8

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma.

Linnemann C, van Buuren MM, Bies L, Verdegaal EM, Schotte R, Calis JJ, Behjati S, Velds A, Hilkmann H, Atmioui DE, Visser M, Stratton MR, Haanen JB, Spits H, van der Burg SH, Schumacher TN. Linnemann C, et al. Nat Med. 2015 Jan;21(1):81-5. doi: 10.1038/nm.3773. Epub 2014 Dec 22. Nat Med. 2015. PMID: 25531942

9

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

Vogel CJ, Smit MA, Maddalo G, Possik PA, Sparidans RW, van der Burg SH, Verdegaal EM, Heck AJ, Samatar AA, Beijnen JH, Altelaar AF, Peeper DS. Vogel CJ, et al. Pigment Cell Melanoma Res. 2015 May;28(3):307-17. doi: 10.1111/pcmr.12364. Epub 2015 Apr 6. Pigment Cell Melanoma Res. 2015. PMID: 25728708

10

Adoptive cell therapy: a highly successful individualized therapy for melanoma with great potential for other malignancies.

Verdegaal EM. Verdegaal EM. Curr Opin Immunol. 2016 Apr;39:90-5. doi: 10.1016/j.coi.2016.01.004. Epub 2016 Jan 30. Curr Opin Immunol. 2016. PMID: 26829458 Free article. Review.

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