Zhu L - Search Results

1

Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy.

Lou M, Liu Q, Ren G, Zeng J, Xiang X, Ding Y, Lin Q, Zhong T, Liu X, Zhu L, Qi H, Shen J, Li H, Shao J. Lou M, et al. Among authors: zhu l. J Biol Chem. 2017 Jun 2;292(22):9136-9149. doi: 10.1074/jbc.M117.783365. Epub 2017 Apr 14. J Biol Chem. 2017. PMID: 28411237 Free PMC article.

2

In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.

Shao J, Zhou B, Zhu L, Qiu W, Yuan YC, Xi B, Yen Y. Shao J, et al. Among authors: zhu l. Cancer Res. 2004 Jan 1;64(1):1-6. doi: 10.1158/0008-5472.can-03-3048. Cancer Res. 2004. PMID: 14729598

3

Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay.

Shao J, Zhou B, Zhu L, Bilio AJ, Su L, Yuan YC, Ren S, Lien EJ, Shih J, Yen Y. Shao J, et al. Among authors: zhu l. Biochem Pharmacol. 2005 Feb 15;69(4):627-34. doi: 10.1016/j.bcp.2004.11.016. Epub 2005 Jan 8. Biochem Pharmacol. 2005. PMID: 15670581

4

A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase.

Shao J, Zhou B, Di Bilio AJ, Zhu L, Wang T, Qi C, Shih J, Yen Y. Shao J, et al. Among authors: zhu l. Mol Cancer Ther. 2006 Mar;5(3):586-92. doi: 10.1158/1535-7163.MCT-05-0384. Mol Cancer Ther. 2006. PMID: 16546972

5

Inhibitory mechanisms of heterocyclic carboxaldehyde thiosemicabazones for two forms of human ribonucleotide reductase.

Zhu L, Zhou B, Chen X, Jiang H, Shao J, Yen Y. Zhu L, et al. Biochem Pharmacol. 2009 Nov 1;78(9):1178-85. doi: 10.1016/j.bcp.2009.06.103. Epub 2009 Jul 2. Biochem Pharmacol. 2009. PMID: 19576866

6

Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine.

Qi H, Zhu H, Lou M, Fan Y, Liu H, Shen J, Li Z, Lv X, Shan J, Zhu L, Chin YE, Shao J. Qi H, et al. Among authors: zhu h, zhu l. J Biol Chem. 2012 Apr 13;287(16):12622-33. doi: 10.1074/jbc.M111.313429. Epub 2012 Feb 24. J Biol Chem. 2012. PMID: 22367195 Free PMC article.

7

Targeting ribonucleotide reductase for cancer therapy.

Shao J, Liu X, Zhu L, Yen Y. Shao J, et al. Among authors: zhu l. Expert Opin Ther Targets. 2013 Dec;17(12):1423-37. doi: 10.1517/14728222.2013.840293. Epub 2013 Oct 1. Expert Opin Ther Targets. 2013. PMID: 24083455 Review.

8

The conserved Lys-95 charged residue cluster is critical for the homodimerization and enzyme activity of human ribonucleotide reductase small subunit M2.

Chen X, Xu Z, Zhang L, Liu H, Liu X, Lou M, Zhu L, Huang B, Yang CG, Zhu W, Shao J. Chen X, et al. Among authors: zhu w, zhu l. J Biol Chem. 2014 Jan 10;289(2):909-20. doi: 10.1074/jbc.M113.524546. Epub 2013 Nov 19. J Biol Chem. 2014. PMID: 24253041 Free PMC article.

9

Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis.

Qi H, Lou M, Chen Y, Liu X, Chen N, Shan J, Ling Z, Shen J, Zhu L, Yen Y, Zheng S, Shao J. Qi H, et al. Among authors: zhu l. Tumour Biol. 2015 Jun;36(6):4833-42. doi: 10.1007/s13277-015-3137-4. Epub 2015 Feb 1. Tumour Biol. 2015. PMID: 25638032

10

Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition.

Liu H, Ren G, Wang T, Chen Y, Gong C, Bai Y, Wang B, Qi H, Shen J, Zhu L, Qian C, Lai M, Shao J. Liu H, et al. Among authors: zhu l. Carcinogenesis. 2015 Apr;36(4):459-68. doi: 10.1093/carcin/bgv017. Epub 2015 Mar 6. Carcinogenesis. 2015. PMID: 25750173 Free PMC article.

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