Stein RW - Search Results

1

Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.

Hunter CS, Stein RW. Hunter CS, et al. Among authors: stein rw. Front Genet. 2017 Mar 29;8:35. doi: 10.3389/fgene.2017.00035. eCollection 2017. Front Genet. 2017. PMID: 28424732 Free PMC article. Review.

2

Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.

Du A, Hunter CS, Murray J, Noble D, Cai CL, Evans SM, Stein R, May CL. Du A, et al. Diabetes. 2009 Sep;58(9):2059-69. doi: 10.2337/db08-0987. Epub 2009 Jun 5. Diabetes. 2009. PMID: 19502415 Free PMC article.

3

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R. Raum JC, et al. Mol Cell Biol. 2010 Sep;30(17):4234-44. doi: 10.1128/MCB.01396-09. Epub 2010 Jun 28. Mol Cell Biol. 2010. PMID: 20584984 Free PMC article.

4

Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.

Hunter CS, Maestro MA, Raum JC, Guo M, Thompson FH 3rd, Ferrer J, Stein R. Hunter CS, et al. Mol Endocrinol. 2011 Feb;25(2):339-47. doi: 10.1210/me.2010-0362. Epub 2010 Dec 30. Mol Endocrinol. 2011. PMID: 21193557 Free PMC article.

5

Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development.

Liu J, Hunter CS, Du A, Ediger B, Walp E, Murray J, Stein R, May CL. Liu J, et al. J Biol Chem. 2011 Apr 29;286(17):15352-60. doi: 10.1074/jbc.M111.231670. Epub 2011 Mar 9. J Biol Chem. 2011. PMID: 21388963 Free PMC article.

6

Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.

Hunter CS, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, Westphal H, Stein R, May CL. Hunter CS, et al. Diabetes. 2013 Mar;62(3):875-86. doi: 10.2337/db12-0952. Epub 2012 Nov 27. Diabetes. 2013. PMID: 23193182 Free PMC article.

7

Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes.

Hunter CS, Stein R. Hunter CS, et al. J Biol Chem. 2013 Feb 8;288(6):3795-803. doi: 10.1074/jbc.M112.434282. Epub 2012 Dec 26. J Biol Chem. 2013. PMID: 23269676 Free PMC article.

8

Revealing transcription factors during human pancreatic β cell development.

Conrad E, Stein R, Hunter CS. Conrad E, et al. Trends Endocrinol Metab. 2014 Aug;25(8):407-14. doi: 10.1016/j.tem.2014.03.013. Epub 2014 May 12. Trends Endocrinol Metab. 2014. PMID: 24831984 Free PMC article. Review.

9

Islet-1 Is essential for pancreatic β-cell function.

Ediger BN, Du A, Liu J, Hunter CS, Walp ER, Schug J, Kaestner KH, Stein R, Stoffers DA, May CL. Ediger BN, et al. Diabetes. 2014 Dec;63(12):4206-17. doi: 10.2337/db14-0096. Epub 2014 Jul 15. Diabetes. 2014. PMID: 25028525 Free PMC article.

10

Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.

Maganti AV, Maier B, Tersey SA, Sampley ML, Mosley AL, Özcan S, Pachaiyappan B, Woster PM, Hunter CS, Stein R, Mirmira RG. Maganti AV, et al. J Biol Chem. 2015 Apr 10;290(15):9812-22. doi: 10.1074/jbc.M114.616219. Epub 2015 Feb 24. J Biol Chem. 2015. PMID: 25713082 Free PMC article.

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