Rash LD - Search Results

1

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.

Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, Rash LD. Wingerd JS, et al. Among authors: rash ld. Sci Rep. 2017 Apr 20;7(1):974. doi: 10.1038/s41598-017-01129-0. Sci Rep. 2017. PMID: 28428547 Free PMC article.

2

Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.

Bosmans F, Rash L, Zhu S, Diochot S, Lazdunski M, Escoubas P, Tytgat J. Bosmans F, et al. Mol Pharmacol. 2006 Feb;69(2):419-29. doi: 10.1124/mol.105.015941. Epub 2005 Nov 2. Mol Pharmacol. 2006. PMID: 16267209

3

Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3.

Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. Jensen JE, et al. Among authors: rash ld. Toxicon. 2009 Jul;54(1):56-61. doi: 10.1016/j.toxicon.2009.03.014. Epub 2009 Mar 21. Toxicon. 2009. PMID: 19306891

4

Venomics: a new paradigm for natural products-based drug discovery.

Vetter I, Davis JL, Rash LD, Anangi R, Mobli M, Alewood PF, Lewis RJ, King GF. Vetter I, et al. Among authors: rash ld. Amino Acids. 2011 Jan;40(1):15-28. doi: 10.1007/s00726-010-0516-4. Epub 2010 Feb 24. Amino Acids. 2011. PMID: 20177945 Review.

5

De novo sequencing of peptides from the parotid secretion of the cane toad, Bufo marinus (Rhinella marina).

Rash LD, Morales RA, Vink S, Alewood PF. Rash LD, et al. Toxicon. 2011 Feb;57(2):208-16. doi: 10.1016/j.toxicon.2010.11.012. Epub 2010 Nov 27. Toxicon. 2011. PMID: 21115026

6

A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a.

Saez NJ, Mobli M, Bieri M, Chassagnon IR, Malde AK, Gamsjaeger R, Mark AE, Gooley PR, Rash LD, King GF. Saez NJ, et al. Among authors: rash ld. Mol Pharmacol. 2011 Nov;80(5):796-808. doi: 10.1124/mol.111.072207. Epub 2011 Aug 8. Mol Pharmacol. 2011. PMID: 21825095

7

Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3.

Jensen JE, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Jensen JE, et al. Among authors: rash ld. Mar Drugs. 2012 Jul;10(7):1511-1527. doi: 10.3390/md10071511. Epub 2012 Jul 16. Mar Drugs. 2012. PMID: 22851922 Free PMC article.

8

Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3.

Anangi R, Rash LD, Mobli M, King GF. Anangi R, et al. Among authors: rash ld. Mar Drugs. 2012 Jul;10(7):1605-1618. doi: 10.3390/md10071605. Epub 2012 Jul 23. Mar Drugs. 2012. PMID: 22851929 Free PMC article.

9

Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli.

Klint JK, Senff S, Saez NJ, Seshadri R, Lau HY, Bende NS, Undheim EA, Rash LD, Mobli M, King GF. Klint JK, et al. Among authors: rash ld. PLoS One. 2013 May 7;8(5):e63865. doi: 10.1371/journal.pone.0063865. Print 2013. PLoS One. 2013. PMID: 23667680 Free PMC article.

10

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.

Schroeder CI, Rash LD, Vila-Farrés X, Rosengren KJ, Mobli M, King GF, Alewood PF, Craik DJ, Durek T. Schroeder CI, et al. Among authors: rash ld. Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1017-20. doi: 10.1002/anie.201308898. Epub 2013 Dec 9. Angew Chem Int Ed Engl. 2014. PMID: 24323786

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