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The immunoproteasome is induced by cytokines and regulates apoptosis in human islets.
Lundh M, Bugliani M, Dahlby T, Chou DH, Wagner B, Ghiasi SM, De Tata V, Chen Z, Lund MN, Davies MJ, Marchetti P, Mandrup-Poulsen T. Lundh M, et al. Among authors: bugliani m. J Endocrinol. 2017 Jun;233(3):369-379. doi: 10.1530/JOE-17-0110. Epub 2017 Apr 24. J Endocrinol. 2017. PMID: 28438776 Free PMC article.
Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.
Bugliani M, Liechti R, Cheon H, Suleiman M, Marselli L, Kirkpatrick C, Filipponi F, Boggi U, Xenarios I, Syed F, Ladriere L, Wollheim C, Lee MS, Marchetti P. Bugliani M, et al. Mol Cell Endocrinol. 2013 Mar 10;367(1-2):1-10. doi: 10.1016/j.mce.2012.12.001. Epub 2012 Dec 12. Mol Cell Endocrinol. 2013. PMID: 23246353
Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans.
Wolden-Kirk H, Rondas D, Bugliani M, Korf H, Van Lommel L, Brusgaard K, Christesen HT, Schuit F, Proost P, Masini M, Marchetti P, Eizirik DL, Overbergh L, Mathieu C. Wolden-Kirk H, et al. Among authors: bugliani m. Endocrinology. 2014 Mar;155(3):736-47. doi: 10.1210/en.2013-1409. Epub 2014 Jan 1. Endocrinology. 2014. PMID: 24424042 Free article.
Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.
Ladrière L, Igoillo-Esteve M, Cunha DA, Brion JP, Bugliani M, Marchetti P, Eizirik DL, Cnop M. Ladrière L, et al. Among authors: bugliani m. J Clin Endocrinol Metab. 2010 Mar;95(3):1442-9. doi: 10.1210/jc.2009-2322. Epub 2010 Jan 15. J Clin Endocrinol Metab. 2010. PMID: 20080856
Mast cells infiltrate pancreatic islets in human type 1 diabetes.
Martino L, Masini M, Bugliani M, Marselli L, Suleiman M, Boggi U, Nogueira TC, Filipponi F, Occhipinti M, Campani D, Dotta F, Syed F, Eizirik DL, Marchetti P, De Tata V. Martino L, et al. Among authors: bugliani m. Diabetologia. 2015 Nov;58(11):2554-62. doi: 10.1007/s00125-015-3734-1. Epub 2015 Aug 15. Diabetologia. 2015. PMID: 26276263
110 results