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The immunoproteasome is induced by cytokines and regulates apoptosis in human islets.
Lundh M, Bugliani M, Dahlby T, Chou DH, Wagner B, Ghiasi SM, De Tata V, Chen Z, Lund MN, Davies MJ, Marchetti P, Mandrup-Poulsen T. Lundh M, et al. Among authors: de tata v. J Endocrinol. 2017 Jun;233(3):369-379. doi: 10.1530/JOE-17-0110. Epub 2017 Apr 24. J Endocrinol. 2017. PMID: 28438776 Free PMC article.
Mast cells infiltrate pancreatic islets in human type 1 diabetes.
Martino L, Masini M, Bugliani M, Marselli L, Suleiman M, Boggi U, Nogueira TC, Filipponi F, Occhipinti M, Campani D, Dotta F, Syed F, Eizirik DL, Marchetti P, De Tata V. Martino L, et al. Among authors: de tata v. Diabetologia. 2015 Nov;58(11):2554-62. doi: 10.1007/s00125-015-3734-1. Epub 2015 Aug 15. Diabetologia. 2015. PMID: 26276263
DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes.
Bugliani M, Syed F, Paula FMM, Omar BA, Suleiman M, Mossuto S, Grano F, Cardarelli F, Boggi U, Vistoli F, Filipponi F, De Simone P, Marselli L, De Tata V, Ahren B, Eizirik DL, Marchetti P. Bugliani M, et al. Among authors: de tata v, de simone p. Mol Cell Endocrinol. 2018 Sep 15;473:186-193. doi: 10.1016/j.mce.2018.01.019. Epub 2018 Feb 1. Mol Cell Endocrinol. 2018. PMID: 29409957
Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes.
Bugliani M, Mossuto S, Grano F, Suleiman M, Marselli L, Boggi U, De Simone P, Eizirik DL, Cnop M, Marchetti P, De Tata V. Bugliani M, et al. Among authors: de tata v, de simone p. Front Endocrinol (Lausanne). 2019 Feb 26;10:52. doi: 10.3389/fendo.2019.00052. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 30863363 Free PMC article.
Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes.
Marchetti P, Bugliani M, De Tata V, Suleiman M, Marselli L. Marchetti P, et al. Among authors: de tata v. Front Cell Dev Biol. 2017 May 23;5:55. doi: 10.3389/fcell.2017.00055. eCollection 2017. Front Cell Dev Biol. 2017. PMID: 28589121 Free PMC article. Review.
81 results