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Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.
Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B. Rollins MF, et al. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5113-E5121. doi: 10.1073/pnas.1616395114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28438998 Free PMC article.
Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteins.
Bondy-Denomy J, Garcia B, Strum S, Du M, Rollins MF, Hidalgo-Reyes Y, Wiedenheft B, Maxwell KL, Davidson AR. Bondy-Denomy J, et al. Nature. 2015 Oct 1;526(7571):136-9. doi: 10.1038/nature15254. Epub 2015 Sep 23. Nature. 2015. PMID: 26416740 Free PMC article.
A Unified Resource for Tracking Anti-CRISPR Names.
Bondy-Denomy J, Davidson AR, Doudna JA, Fineran PC, Maxwell KL, Moineau S, Peng X, Sontheimer EJ, Wiedenheft B. Bondy-Denomy J, et al. CRISPR J. 2018 Oct;1(5):304-305. doi: 10.1089/crispr.2018.0043. CRISPR J. 2018. PMID: 31021273 Free PMC article. No abstract available.
A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases.
Mendoza SD, Nieweglowska ES, Govindarajan S, Leon LM, Berry JD, Tiwari A, Chaikeeratisak V, Pogliano J, Agard DA, Bondy-Denomy J. Mendoza SD, et al. Nature. 2020 Jan;577(7789):244-248. doi: 10.1038/s41586-019-1786-y. Epub 2019 Dec 9. Nature. 2020. PMID: 31819262 Free PMC article.
81 results