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Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.
Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B. Rollins MF, et al. Among authors: wiedenheft b. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5113-E5121. doi: 10.1073/pnas.1616395114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28438998 Free PMC article.
The retrotransposon - derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity.
Wood TWP, Henriques WS, Cullen HB, Romero M, Blengini CS, Sarathy S, Sorkin J, Bekele H, Jin C, Kim S, Chemiakine A, Khondker RC, Isola JVV, Stout MB, Gennarino VA, Mogessie B, Jain D, Schindler K, Suh Y, Wiedenheft B, Berchowitz LE. Wood TWP, et al. Among authors: wiedenheft b. bioRxiv [Preprint]. 2024 May 14:2024.05.11.592987. doi: 10.1101/2024.05.11.592987. bioRxiv. 2024. PMID: 38798495 Free PMC article. Preprint.
Fitting CRISPR-associated Cas3 into the helicase family tree.
Jackson RN, Lavin M, Carter J, Wiedenheft B. Jackson RN, et al. Among authors: wiedenheft b. Curr Opin Struct Biol. 2014 Feb;24:106-14. doi: 10.1016/j.sbi.2014.01.001. Epub 2014 Jan 28. Curr Opin Struct Biol. 2014. PMID: 24480304 Free PMC article. Review.
A CRISPR method for genome engineering.
Wilkinson R, Wiedenheft B. Wilkinson R, et al. Among authors: wiedenheft b. F1000Prime Rep. 2014 Jan 2;6:3. doi: 10.12703/P6-3. eCollection 2014. F1000Prime Rep. 2014. PMID: 24592315 Free PMC article. Review.
The history and market impact of CRISPR RNA-guided nucleases.
van Erp PB, Bloomer G, Wilkinson R, Wiedenheft B. van Erp PB, et al. Among authors: wiedenheft b. Curr Opin Virol. 2015 Jun;12:85-90. doi: 10.1016/j.coviro.2015.03.011. Epub 2015 Apr 26. Curr Opin Virol. 2015. PMID: 25914022 Free PMC article.
89 results