Lal-Nag M - Search Results

1

PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.

Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song Y, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal-Nag M, Ferrer M, Shern JF, Zhao K, Thomas CJ, Khan J. Gryder BE, et al. Cancer Discov. 2017 Aug;7(8):884-899. doi: 10.1158/2159-8290.CD-16-1297. Epub 2017 Apr 26. Cancer Discov. 2017. PMID: 28446439 Free PMC article.

2

A High-Throughput Screening Model of the Tumor Microenvironment for Ovarian Cancer Cell Growth.

Lal-Nag M, McGee L, Guha R, Lengyel E, Kenny HA, Ferrer M. Lal-Nag M, et al. SLAS Discov. 2017 Jun;22(5):494-506. doi: 10.1177/2472555216687082. Epub 2017 Jan 31. SLAS Discov. 2017. PMID: 28346091 Free PMC article.

3

RNAi High-Throughput Screening of Single- and Multi-Cell-Type Tumor Spheroids: A Comprehensive Analysis in Two and Three Dimensions.

Fu J, Fernandez D, Ferrer M, Titus SA, Buehler E, Lal-Nag MA. Fu J, et al. SLAS Discov. 2017 Jun;22(5):525-536. doi: 10.1177/2472555217696796. Epub 2017 Mar 9. SLAS Discov. 2017. PMID: 28277887 Free article.

4

Exploring Drug Dosing Regimens In Vitro Using Real-Time 3D Spheroid Tumor Growth Assays.

Lal-Nag M, McGee L, Titus SA, Brimacombe K, Michael S, Sittampalam G, Ferrer M. Lal-Nag M, et al. SLAS Discov. 2017 Jun;22(5):537-546. doi: 10.1177/2472555217698818. Epub 2017 Mar 15. SLAS Discov. 2017. PMID: 28298153 Free article.

5

Large-scale pharmacological profiling of 3D tumor models of cancer cells.

Mathews Griner LA, Zhang X, Guha R, McKnight C, Goldlust IS, Lal-Nag M, Wilson K, Michael S, Titus S, Shinn P, Thomas CJ, Ferrer M. Mathews Griner LA, et al. Cell Death Dis. 2016 Dec 1;7(12):e2492. doi: 10.1038/cddis.2016.360. Cell Death Dis. 2016. PMID: 27906188 Free PMC article.

6

Translational in vitro research: integrating 3D drug discovery and development processes into the drug development pipeline.

Kelm JM, Lal-Nag M, Sittampalam GS, Ferrer M. Kelm JM, et al. Drug Discov Today. 2019 Jan;24(1):26-30. doi: 10.1016/j.drudis.2018.07.007. Epub 2018 Jul 30. Drug Discov Today. 2019. PMID: 30071313

7

Quantitative High-Throughput Screening Using an Organotypic Model Identifies Compounds that Inhibit Ovarian Cancer Metastasis.

Kenny HA, Lal-Nag M, Shen M, Kara B, Nahotko DA, Wroblewski K, Fazal S, Chen S, Chiang CY, Chen YJ, Brimacombe KR, Marugan J, Ferrer M, Lengyel E. Kenny HA, et al. Mol Cancer Ther. 2020 Jan;19(1):52-62. doi: 10.1158/1535-7163.MCT-19-0052. Epub 2019 Sep 27. Mol Cancer Ther. 2020. PMID: 31562255 Free PMC article.

8

A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells.

Weydert Z, Lal-Nag M, Mathews-Greiner L, Thiel C, Cordes H, Küpfer L, Guye P, Kelm JM, Ferrer M. Weydert Z, et al. SLAS Discov. 2020 Mar;25(3):265-276. doi: 10.1177/2472555219880194. Epub 2019 Oct 29. SLAS Discov. 2020. PMID: 31658853 Free PMC article.

9

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer M, Lengyel E. Kenny HA, et al. Nat Commun. 2015 Feb 5;6:6220. doi: 10.1038/ncomms7220. Nat Commun. 2015. PMID: 25653139 Free PMC article.

10

Microfluidic Mobility Shift Profiling of Lysine Acetyltransferases Enables Screening and Mechanistic Analysis of Cellular Acetylation Inhibitors.

Sorum AW, Shrimp JH, Roberts AM, Montgomery DC, Tiwari NK, Lal-Nag M, Simeonov A, Jadhav A, Meier JL. Sorum AW, et al. ACS Chem Biol. 2016 Mar 18;11(3):734-41. doi: 10.1021/acschembio.5b00709. Epub 2015 Oct 14. ACS Chem Biol. 2016. PMID: 26428393 Free PMC article.

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