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PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.
Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song Y, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal-Nag M, Ferrer M, Shern JF, Zhao K, Thomas CJ, Khan J. Gryder BE, et al. Among authors: rota r. Cancer Discov. 2017 Aug;7(8):884-899. doi: 10.1158/2159-8290.CD-16-1297. Epub 2017 Apr 26. Cancer Discov. 2017. PMID: 28446439 Free PMC article.
DNA repair in tumor radioresistance: insights from fruit flies genetics.
Porrazzo A, Cassandri M, D'Alessandro A, Morciano P, Rota R, Marampon F, Cenci G. Porrazzo A, et al. Among authors: rota r. Cell Oncol (Dordr). 2024 Jun;47(3):717-732. doi: 10.1007/s13402-023-00906-6. Epub 2023 Dec 14. Cell Oncol (Dordr). 2024. PMID: 38095764 Review.
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.
Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini PP, Dall'agnese A, Verginelli F, Milano GM, Boldrini R, Inserra A, Stifani S, Screpanti I, Marquez VE, Valente S, Mai A, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: rota r. BMC Cancer. 2014 Feb 27;14:139. doi: 10.1186/1471-2407-14-139. BMC Cancer. 2014. PMID: 24575771 Free PMC article.
Rhabdomyosarcoma: current challenges and their implications for developing therapies.
Hettmer S, Li Z, Billin AN, Barr FG, Cornelison DD, Ehrlich AR, Guttridge DC, Hayes-Jordan A, Helman LJ, Houghton PJ, Khan J, Langenau DM, Linardic CM, Pal R, Partridge TA, Pavlath GK, Rota R, Schäfer BW, Shipley J, Stillman B, Wexler LH, Wagers AJ, Keller C. Hettmer S, et al. Among authors: rota r. Cold Spring Harb Perspect Med. 2014 Nov 3;4(11):a025650. doi: 10.1101/cshperspect.a025650. Cold Spring Harb Perspect Med. 2014. PMID: 25368019 Free PMC article. Review.
Insights into pediatric rhabdomyosarcoma research: Challenges and goals.
Yohe ME, Heske CM, Stewart E, Adamson PC, Ahmed N, Antonescu CR, Chen E, Collins N, Ehrlich A, Galindo RL, Gryder BE, Hahn H, Hammond S, Hatley ME, Hawkins DS, Hayes MN, Hayes-Jordan A, Helman LJ, Hettmer S, Ignatius MS, Keller C, Khan J, Kirsch DG, Linardic CM, Lupo PJ, Rota R, Shern JF, Shipley J, Sindiri S, Tapscott SJ, Vakoc CR, Wexler LH, Langenau DM. Yohe ME, et al. Among authors: rota r. Pediatr Blood Cancer. 2019 Oct;66(10):e27869. doi: 10.1002/pbc.27869. Epub 2019 Jun 21. Pediatr Blood Cancer. 2019. PMID: 31222885 Free PMC article. Review.
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma.
Gryder BE, Pomella S, Sayers C, Wu XS, Song Y, Chiarella AM, Bagchi S, Chou HC, Sinniah RS, Walton A, Wen X, Rota R, Hathaway NA, Zhao K, Chen J, Vakoc CR, Shern JF, Stanton BZ, Khan J. Gryder BE, et al. Among authors: rota r. Nat Genet. 2019 Dec;51(12):1714-1722. doi: 10.1038/s41588-019-0534-4. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784732 Free PMC article.
The CRISP(Y) Future of Pediatric Soft Tissue Sarcomas.
Pomella S, Rota R. Pomella S, et al. Among authors: rota r. Front Chem. 2020 Mar 13;8:178. doi: 10.3389/fchem.2020.00178. eCollection 2020. Front Chem. 2020. PMID: 32232030 Free PMC article. Review.
Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage.
Gryder BE, Wachtel M, Chang K, El Demerdash O, Aboreden NG, Mohammed W, Ewert W, Pomella S, Rota R, Wei JS, Song Y, Stanton BZ, Schäfer B, Vakoc CR, Khan J. Gryder BE, et al. Among authors: rota r. iScience. 2020 May 22;23(5):101103. doi: 10.1016/j.isci.2020.101103. Epub 2020 Apr 29. iScience. 2020. PMID: 32416589 Free PMC article.
134 results