Royer WE - Search Results

1

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.

Kouno T, Silvas TV, Hilbert BJ, Shandilya SMD, Bohn MF, Kelch BA, Royer WE, Somasundaran M, Kurt Yilmaz N, Matsuo H, Schiffer CA. Kouno T, et al. Among authors: royer we. Nat Commun. 2017 Apr 28;8:15024. doi: 10.1038/ncomms15024. Nat Commun. 2017. PMID: 28452355 Free PMC article.

2

Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.

Shandilya SM, Nalam MN, Nalivaika EA, Gross PJ, Valesano JC, Shindo K, Li M, Munson M, Royer WE, Harjes E, Kono T, Matsuo H, Harris RS, Somasundaran M, Schiffer CA. Shandilya SM, et al. Among authors: royer we. Structure. 2010 Jan 13;18(1):28-38. doi: 10.1016/j.str.2009.10.016. Structure. 2010. PMID: 20152150 Free PMC article.

3

Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.

Chen W, Lam SS, Srinath H, Jiang Z, Correia JJ, Schiffer CA, Fitzgerald KA, Lin K, Royer WE Jr. Chen W, et al. Among authors: royer we jr. Nat Struct Mol Biol. 2008 Nov;15(11):1213-20. doi: 10.1038/nsmb.1496. Epub 2008 Oct 5. Nat Struct Mol Biol. 2008. PMID: 18836453 Free PMC article.

4

Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding.

Romano KP, Ali A, Royer WE, Schiffer CA. Romano KP, et al. Among authors: royer we. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20986-91. doi: 10.1073/pnas.1006370107. Epub 2010 Nov 17. Proc Natl Acad Sci U S A. 2010. PMID: 21084633 Free PMC article.

5

Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.

Hilbert BJ, Grossman SR, Schiffer CA, Royer WE Jr. Hilbert BJ, et al. Among authors: royer we jr. FEBS Lett. 2014 May 2;588(9):1743-8. doi: 10.1016/j.febslet.2014.03.026. Epub 2014 Mar 19. FEBS Lett. 2014. PMID: 24657618 Free PMC article.

6

Structure-guided design of a high affinity inhibitor to human CtBP.

Hilbert BJ, Morris BL, Ellis KC, Paulsen JL, Schiffer CA, Grossman SR, Royer WE Jr. Hilbert BJ, et al. Among authors: royer we jr. ACS Chem Biol. 2015 Apr 17;10(4):1118-27. doi: 10.1021/cb500820b. Epub 2015 Jan 30. ACS Chem Biol. 2015. PMID: 25636004 Free PMC article.

7

NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).

Nichols JC, Schiffer CA, Royer WE Jr. Nichols JC, et al. Among authors: royer we jr. J Biol Chem. 2021 Jan-Jun;296:100351. doi: 10.1016/j.jbc.2021.100351. Epub 2021 Jan 30. J Biol Chem. 2021. PMID: 33524397 Free PMC article.

8

Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-beta signaling.

Chen W, Lam SS, Srinath H, Schiffer CA, Royer WE Jr, Lin K. Chen W, et al. Among authors: royer we jr. J Biol Chem. 2007 Apr 13;282(15):11365-76. doi: 10.1074/jbc.M700186200. Epub 2007 Feb 5. J Biol Chem. 2007. PMID: 17283070 Free article.

9

Assembly of human C-terminal binding protein (CtBP) into tetramers.

Bellesis AG, Jecrois AM, Hayes JA, Schiffer CA, Royer WE Jr. Bellesis AG, et al. Among authors: royer we jr. J Biol Chem. 2018 Jun 8;293(23):9101-9112. doi: 10.1074/jbc.RA118.002514. Epub 2018 Apr 26. J Biol Chem. 2018. PMID: 29700119 Free PMC article.

10

Optimizing the refinement of merohedrally twinned P6₁ HIV-1 protease-inhibitor cocrystal structures.

Lockbaum GJ, Leidner F, Royer WE, Kurt Yilmaz N, Schiffer CA. Lockbaum GJ, et al. Among authors: royer we. Acta Crystallogr D Struct Biol. 2020 Mar 1;76(Pt 3):302-310. doi: 10.1107/S2059798320001989. Epub 2020 Mar 2. Acta Crystallogr D Struct Biol. 2020. PMID: 32133994 Free PMC article.

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