Jaeschke H - Search Results

1

Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated Mice.

Li J, Woolbright BL, Zhao W, Wang Y, Matye D, Hagenbuch B, Jaeschke H, Li T. Li J, et al. Among authors: jaeschke h. Toxicol Sci. 2018 Jan 1;161(1):34-47. doi: 10.1093/toxsci/kfx078. Toxicol Sci. 2018. PMID: 28453831 Free PMC article.

2

Differential effect of 2-aminoethyl-isothiourea, an inhibitor of the inducible nitric oxide synthase, on microvascular blood flow and organ injury in models of hepatic ischemia-reperfusion and endotoxemia.

Wang Y, Lawson JA, Jaeschke H. Wang Y, et al. Among authors: jaeschke h. Shock. 1998 Jul;10(1):20-5. doi: 10.1097/00024382-199807000-00004. Shock. 1998. PMID: 9688086

3

Mechanisms of hepatotoxicity.

Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Jaeschke H, et al. Toxicol Sci. 2002 Feb;65(2):166-76. doi: 10.1093/toxsci/65.2.166. Toxicol Sci. 2002. PMID: 11812920 Review.

4

Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice.

Gujral JS, Farhood A, Bajt ML, Jaeschke H. Gujral JS, et al. Among authors: jaeschke h. Hepatology. 2003 Aug;38(2):355-63. doi: 10.1053/jhep.2003.50341. Hepatology. 2003. PMID: 12883479

5

Troglitazone hepatotoxicity: are we getting closer to understanding idiosyncratic liver injury?

Jaeschke H. Jaeschke H. Toxicol Sci. 2007 May;97(1):1-3. doi: 10.1093/toxsci/kfm021. Toxicol Sci. 2007. PMID: 17575588 No abstract available.

6

Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice.

Williams CD, Bajt ML, Farhood A, Jaeschke H. Williams CD, et al. Among authors: jaeschke h. Liver Int. 2010 Oct;30(9):1280-92. doi: 10.1111/j.1478-3231.2010.02284.x. Liver Int. 2010. PMID: 20500806 Free PMC article.

7

The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes.

Yan HM, Ramachandran A, Bajt ML, Lemasters JJ, Jaeschke H. Yan HM, et al. Among authors: jaeschke h. Toxicol Sci. 2010 Oct;117(2):515-23. doi: 10.1093/toxsci/kfq208. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616211 Free PMC article.

8

Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury.

Williams CD, Farhood A, Jaeschke H. Williams CD, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Sep 15;247(3):169-78. doi: 10.1016/j.taap.2010.07.004. Epub 2010 Jul 15. Toxicol Appl Pharmacol. 2010. PMID: 20637792 Free PMC article.

9

Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.

Allen K, Jaeschke H, Copple BL. Allen K, et al. Among authors: jaeschke h. Am J Pathol. 2011 Jan;178(1):175-86. doi: 10.1016/j.ajpath.2010.11.026. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224055 Free PMC article.

10

Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.

Bajt ML, Ramachandran A, Yan HM, Lebofsky M, Farhood A, Lemasters JJ, Jaeschke H. Bajt ML, et al. Among authors: jaeschke h. Toxicol Sci. 2011 Aug;122(2):598-605. doi: 10.1093/toxsci/kfr116. Epub 2011 May 13. Toxicol Sci. 2011. PMID: 21572097 Free PMC article.

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