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PTP1B deficiency improves hypothalamic insulin sensitivity resulting in the attenuation of AgRP mRNA expression under high-fat diet conditions.
Sugiyama M, Banno R, Mizoguchi A, Tominaga T, Tsunekawa T, Onoue T, Hagiwara D, Ito Y, Morishita Y, Iwama S, Goto M, Suga H, Arima H. Sugiyama M, et al. Among authors: ito y. Biochem Biophys Res Commun. 2017 Jun 17;488(1):116-121. doi: 10.1016/j.bbrc.2017.05.019. Epub 2017 May 4. Biochem Biophys Res Commun. 2017. PMID: 28479249
AgRP Neuron-Specific Deletion of Glucocorticoid Receptor Leads to Increased Energy Expenditure and Decreased Body Weight in Female Mice on a High-Fat Diet.
Shibata M, Banno R, Sugiyama M, Tominaga T, Onoue T, Tsunekawa T, Azuma Y, Hagiwara D, Lu W, Ito Y, Goto M, Suga H, Sugimura Y, Oiso Y, Arima H. Shibata M, et al. Among authors: ito y. Endocrinology. 2016 Apr;157(4):1457-66. doi: 10.1210/en.2015-1430. Epub 2016 Feb 18. Endocrinology. 2016. PMID: 26889940
Hypothalamic glial cells isolated by MACS reveal that microglia and astrocytes induce hypothalamic inflammation via different processes under high-fat diet conditions.
Sugiyama M, Banno R, Yaginuma H, Taki K, Mizoguchi A, Tsunekawa T, Onoue T, Takagi H, Ito Y, Iwama S, Goto M, Suga H, Komine O, Yamanaka K, Arima H. Sugiyama M, et al. Among authors: ito y. Neurochem Int. 2020 Jun;136:104733. doi: 10.1016/j.neuint.2020.104733. Epub 2020 Mar 25. Neurochem Int. 2020. PMID: 32222288
Dietary sodium chloride attenuates increased β-cell mass to cause glucose intolerance in mice under a high-fat diet.
Taki K, Takagi H, Hirose T, Sun R, Yaginuma H, Mizoguchi A, Kobayashi T, Sugiyama M, Tsunekawa T, Onoue T, Hagiwara D, Ito Y, Iwama S, Suga H, Banno R, Sakano D, Kume S, Arima H. Taki K, et al. Among authors: ito y. PLoS One. 2021 Mar 17;16(3):e0248065. doi: 10.1371/journal.pone.0248065. eCollection 2021. PLoS One. 2021. PMID: 33730054 Free PMC article.
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