Cooper RA - Search Results

1

A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine.

Dhingra SK, Redhi D, Combrinck JM, Yeo T, Okombo J, Henrich PP, Cowell AN, Gupta P, Stegman ML, Hoke JM, Cooper RA, Winzeler E, Mok S, Egan TJ, Fidock DA. Dhingra SK, et al. Among authors: cooper ra. mBio. 2017 May 9;8(3):e00303-17. doi: 10.1128/mBio.00303-17. mBio. 2017. PMID: 28487425 Free PMC article.

2

P. falciparum CG2, linked to chloroquine resistance, does not resemble Na+/H+ exchangers.

Wellems TE, Wootton JC, Fujioka H, Su X, Cooper R, Baruch D, Fidock DA. Wellems TE, et al. Cell. 1998 Aug 7;94(3):285-6. doi: 10.1016/s0092-8674(00)81471-3. Cell. 1998. PMID: 9708730 Free article. No abstract available.

3

Allelic modifications of the cg2 and cg1 genes do not alter the chloroquine response of drug-resistant Plasmodium falciparum.

Fidock DA, Nomura T, Cooper RA, Su X, Talley AK, Wellems TE. Fidock DA, et al. Among authors: cooper ra. Mol Biochem Parasitol. 2000 Sep;110(1):1-10. doi: 10.1016/s0166-6851(00)00249-8. Mol Biochem Parasitol. 2000. PMID: 10989140

4

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naudé B, Deitsch KW, Su XZ, Wootton JC, Roepe PD, Wellems TE. Fidock DA, et al. Among authors: cooper ra. Mol Cell. 2000 Oct;6(4):861-71. doi: 10.1016/s1097-2765(05)00077-8. Mol Cell. 2000. PMID: 11090624 Free PMC article.

5

Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.

Cooper RA, Ferdig MT, Su XZ, Ursos LM, Mu J, Nomura T, Fujioka H, Fidock DA, Roepe PD, Wellems TE. Cooper RA, et al. Mol Pharmacol. 2002 Jan;61(1):35-42. doi: 10.1124/mol.61.1.35. Mol Pharmacol. 2002. PMID: 11752204

6

Proteomic approaches to studying drug targets and resistance in Plasmodium.

Cooper RA, Carucci DJ. Cooper RA, et al. Curr Drug Targets Infect Disord. 2004 Mar;4(1):41-51. doi: 10.2174/1568005043480989. Curr Drug Targets Infect Disord. 2004. PMID: 15032633 Review.

7

pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective.

Cooper RA, Hartwig CL, Ferdig MT. Cooper RA, et al. Acta Trop. 2005 Jun;94(3):170-80. doi: 10.1016/j.actatropica.2005.04.004. Acta Trop. 2005. PMID: 15866507 Review.

8

Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.

Cooper RA, Lane KD, Deng B, Mu J, Patel JJ, Wellems TE, Su X, Ferdig MT. Cooper RA, et al. Mol Microbiol. 2007 Jan;63(1):270-82. doi: 10.1111/j.1365-2958.2006.05511.x. Epub 2006 Dec 5. Mol Microbiol. 2007. PMID: 17163969 Free article.

9

Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes.

Hartwig CL, Lauterwasser EM, Mahajan SS, Hoke JM, Cooper RA, Renslo AR. Hartwig CL, et al. Among authors: cooper ra. J Med Chem. 2011 Dec 8;54(23):8207-13. doi: 10.1021/jm2012003. Epub 2011 Nov 9. J Med Chem. 2011. PMID: 22023506 Free PMC article.

10

Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids.

Griffin CE, Hoke JM, Samarakoon U, Duan J, Mu J, Ferdig MT, Warhurst DC, Cooper RA. Griffin CE, et al. Among authors: cooper ra. Antimicrob Agents Chemother. 2012 Oct;56(10):5356-64. doi: 10.1128/AAC.05667-11. Epub 2012 Aug 6. Antimicrob Agents Chemother. 2012. PMID: 22869567 Free PMC article.

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