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Low-Dose Aspirin Acetylates Cyclooxygenase-1 in Human Colorectal Mucosa: Implications for the Chemoprevention of Colorectal Cancer.
Patrignani P, Sacco A, Sostres C, Bruno A, Dovizio M, Piazuelo E, Di Francesco L, Contursi A, Zucchelli M, Schiavone S, Tacconelli S, Patrono C, Lanas A. Patrignani P, et al. Among authors: contursi a. Clin Pharmacol Ther. 2017 Jul;102(1):52-61. doi: 10.1002/cpt.639. Epub 2017 Apr 4. Clin Pharmacol Ther. 2017. PMID: 28139830 Clinical Trial.
Therapeutic targeting of dysregulated cellular communication.
Schiavone S, Contursi A, Grande R, Patrignani P. Schiavone S, et al. Among authors: contursi a. Ann Transl Med. 2017 May;5(10):222. doi: 10.21037/atm.2017.03.62. Ann Transl Med. 2017. PMID: 28603737 Free PMC article. No abstract available.
Antithrombotic Agents and Cancer.
Bruno A, Dovizio M, Tacconelli S, Contursi A, Ballerini P, Patrignani P. Bruno A, et al. Among authors: contursi a. Cancers (Basel). 2018 Jul 31;10(8):253. doi: 10.3390/cancers10080253. Cancers (Basel). 2018. PMID: 30065215 Free PMC article. Review.
Platelets in cancer development and diagnosis.
Contursi A, Grande R, Dovizio M, Bruno A, Fullone R, Patrignani P. Contursi A, et al. Biochem Soc Trans. 2018 Dec 17;46(6):1517-1527. doi: 10.1042/BST20180159. Epub 2018 Nov 12. Biochem Soc Trans. 2018. PMID: 30420412 Review.
miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction.
Saul MJ, Baumann I, Bruno A, Emmerich AC, Wellstein J, Ottinger SM, Contursi A, Dovizio M, Donnini S, Tacconelli S, Raouf J, Idborg H, Stein S, Korotkova M, Savai R, Terzuoli E, Sala G, Seeger W, Jakobsson PJ, Patrignani P, Suess B, Steinhilber D. Saul MJ, et al. Among authors: contursi a. FASEB J. 2019 Jun;33(6):6933-6947. doi: 10.1096/fj.201802547R. Epub 2019 Mar 28. FASEB J. 2019. PMID: 30922080
Moreover, miR-574-5p is induced by IL-1beta and is strongly overexpressed in human nonsmall cell lung cancer where high mPGES-1 expression correlates with a low survival rate. The discovered function of miR-574-5p as a CUGBP1 decoy opens up new therapeutic opportuni …
Moreover, miR-574-5p is induced by IL-1beta and is strongly overexpressed in human nonsmall cell lung cancer where high mPGES-1 expression c …
Platelet-Specific Deletion of Cyclooxygenase-1 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice.
Sacco A, Bruno A, Contursi A, Dovizio M, Tacconelli S, Ricciotti E, Guillem-Llobat P, Salvatore T, Di Francesco L, Fullone R, Ballerini P, Arena V, Alberti S, Liu G, Gong Y, Sgambato A, Patrono C, FitzGerald GA, Yu Y, Patrignani P. Sacco A, et al. Among authors: contursi a. J Pharmacol Exp Ther. 2019 Sep;370(3):416-426. doi: 10.1124/jpet.119.259382. Epub 2019 Jun 27. J Pharmacol Exp Ther. 2019. PMID: 31248980
Pharmacological characterization of the biosynthesis of prostanoids and hydroxyeicosatetraenoic acids in human whole blood and platelets by targeted chiral lipidomics analysis.
Tacconelli S, Fullone R, Dovizio M, Pizzicoli G, Marschler S, Bruno A, Zucchelli M, Contursi A, Ballerini P, Patrignani P. Tacconelli S, et al. Among authors: contursi a. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Dec;1865(12):158804. doi: 10.1016/j.bbalip.2020.158804. Epub 2020 Aug 25. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32853794
32 results