Bosma PJ - Search Results

1

Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo.

van Dijk R, Aronson SJ, de Waart DR, van de Graaf SF, Duijst S, Seppen J, Elferink RO, Beuers U, Bosma PJ. van Dijk R, et al. Among authors: bosma pj. Sci Rep. 2017 May 10;7(1):1646. doi: 10.1038/s41598-017-01602-w. Sci Rep. 2017. PMID: 28490767 Free PMC article.

2

Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase.

Seppen J, Bosma PJ, Goldhoorn BG, Bakker CT, Chowdhury JR, Chowdhury NR, Jansen PL, Oude Elferink RP. Seppen J, et al. Among authors: bosma pj. J Clin Invest. 1994 Dec;94(6):2385-91. doi: 10.1172/JCI117604. J Clin Invest. 1994. PMID: 7989595 Free PMC article.

3

Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man.

Bosma PJ, Seppen J, Goldhoorn B, Bakker C, Oude Elferink RP, Chowdhury JR, Chowdhury NR, Jansen PL. Bosma PJ, et al. J Biol Chem. 1994 Jul 8;269(27):17960-4. J Biol Chem. 1994. PMID: 8027054 Free article.

4

Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.

Seppen J, Tada K, Hellwig S, Bakker CT, Prasad VR, Roy Chowdhury N, Roy Chowdhury J, Bosma PJ, Oude Elferink RP. Seppen J, et al. Among authors: bosma pj. Biochem J. 1996 Mar 1;314 ( Pt 2)(Pt 2):477-83. doi: 10.1042/bj3140477. Biochem J. 1996. PMID: 8670060 Free PMC article.

5

A mutation which disrupts the hydrophobic core of the signal peptide of bilirubin UDP-glucuronosyltransferase, an endoplasmic reticulum membrane protein, causes Crigler-Najjar type II.

Seppen J, Steenken E, Lindhout D, Bosma PJ, Elferink RP. Seppen J, et al. Among authors: bosma pj. FEBS Lett. 1996 Jul 29;390(3):294-8. doi: 10.1016/0014-5793(96)00677-1. FEBS Lett. 1996. PMID: 8706880 Free article.

6

Transplantation of Gunn rats with autologous fibroblasts expressing bilirubin UDP-glucuronosyltransferase: correction of genetic deficiency and tumor formation.

Seppen J, Tada K, Ottenhoff R, Sengupta K, Chowdhury NR, Chowdhury JR, Bosma PJ, Oude Elferink RP. Seppen J, et al. Among authors: bosma pj. Hum Gene Ther. 1997 Jan 1;8(1):27-36. doi: 10.1089/hum.1997.8.1-27. Hum Gene Ther. 1997. PMID: 8989992

7

Adeno-associated virus vector serotypes mediate sustained correction of bilirubin UDP glucuronosyltransferase deficiency in rats.

Seppen J, Bakker C, de Jong B, Kunne C, van den Oever K, Vandenberghe K, de Waart R, Twisk J, Bosma P. Seppen J, et al. Mol Ther. 2006 Jun;13(6):1085-92. doi: 10.1016/j.ymthe.2006.01.014. Epub 2006 Apr 3. Mol Ther. 2006. PMID: 16581301 Free article.

8

Transcriptional profiling reveals novel markers of liver fibrogenesis: gremlin and insulin-like growth factor-binding proteins.

Boers W, Aarrass S, Linthorst C, Pinzani M, Elferink RO, Bosma P. Boers W, et al. J Biol Chem. 2006 Jun 16;281(24):16289-95. doi: 10.1074/jbc.M600711200. Epub 2006 Apr 10. J Biol Chem. 2006. PMID: 16606614 Free article.

9

Mycophenolate mofetil impairs transduction of single-stranded adeno-associated viral vectors.

Montenegro-Miranda PS, ten Bloemendaal L, Kunne C, de Waart DR, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: bosma pj. Hum Gene Ther. 2011 May;22(5):605-12. doi: 10.1089/hum.2010.222. Epub 2011 Apr 11. Hum Gene Ther. 2011. PMID: 21222531

10

Overexpression of insulin like growth factor binding protein 5 reduces liver fibrosis in chronic cholangiopathy.

Sokolović A, Montenegro-Miranda PS, de Waart DR, Cappai RM, Duijst S, Sokolović M, Bosma PJ. Sokolović A, et al. Among authors: bosma pj. Biochim Biophys Acta. 2012 Jun;1822(6):996-1003. doi: 10.1016/j.bbadis.2012.02.022. Epub 2012 Mar 13. Biochim Biophys Acta. 2012. PMID: 22434064 Free article.

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