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Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T).
Rothenberg I, Piccini I, Wrobel E, Stallmeyer B, Müller J, Greber B, Strutz-Seebohm N, Schulze-Bahr E, Schmitt N, Seebohm G. Rothenberg I, et al. Among authors: piccini i. HeartRhythm Case Rep. 2016 Sep 12;2(6):521-529. doi: 10.1016/j.hrcr.2016.08.015. eCollection 2016 Nov. HeartRhythm Case Rep. 2016. PMID: 28491751 Free PMC article. No abstract available.
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.
Zhang M, D'Aniello C, Verkerk AO, Wrobel E, Frank S, Ward-van Oostwaard D, Piccini I, Freund C, Rao J, Seebohm G, Atsma DE, Schulze-Bahr E, Mummery CL, Greber B, Bellin M. Zhang M, et al. Among authors: piccini i. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5383-92. doi: 10.1073/pnas.1419553111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453094 Free PMC article.
Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation.
Zhang M, Schulte JS, Heinick A, Piccini I, Rao J, Quaranta R, Zeuschner D, Malan D, Kim KP, Röpke A, Sasse P, Araúzo-Bravo M, Seebohm G, Schöler H, Fabritz L, Kirchhof P, Müller FU, Greber B. Zhang M, et al. Among authors: piccini i. Stem Cells. 2015 May;33(5):1456-69. doi: 10.1002/stem.1964. Stem Cells. 2015. PMID: 25639979
Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs.
Rao J, Pfeiffer MJ, Frank S, Adachi K, Piccini I, Quaranta R, Araúzo-Bravo M, Schwarz J, Schade D, Leidel S, Schöler HR, Seebohm G, Greber B. Rao J, et al. Among authors: piccini i. Cell Stem Cell. 2016 Mar 3;18(3):341-53. doi: 10.1016/j.stem.2015.11.019. Epub 2015 Dec 31. Cell Stem Cell. 2016. PMID: 26748419 Free article.
The Natural Plant Product Rottlerin Activates Kv7.1/KCNE1 Channels.
Matschke V, Piccini I, Schubert J, Wrobel E, Lang F, Matschke J, Amedonu E, Meuth SG, Strünker T, Strutz-Seebohm N, Greber B, Scherkenbeck J, Seebohm G. Matschke V, et al. Among authors: piccini i. Cell Physiol Biochem. 2016;40(6):1549-1558. doi: 10.1159/000453205. Epub 2016 Dec 21. Cell Physiol Biochem. 2016. PMID: 27997884 Free article.
From iPSC towards cardiac tissue-a road under construction.
Peischard S, Piccini I, Strutz-Seebohm N, Greber B, Seebohm G. Peischard S, et al. Among authors: piccini i. Pflugers Arch. 2017 Oct;469(10):1233-1243. doi: 10.1007/s00424-017-2003-1. Epub 2017 Jun 1. Pflugers Arch. 2017. PMID: 28573409 Free PMC article. Review.
48 results