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Page 1
Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T).
Rothenberg I, Piccini I, Wrobel E, Stallmeyer B, Müller J, Greber B, Strutz-Seebohm N, Schulze-Bahr E, Schmitt N, Seebohm G. Rothenberg I, et al. Among authors: wrobel e. HeartRhythm Case Rep. 2016 Sep 12;2(6):521-529. doi: 10.1016/j.hrcr.2016.08.015. eCollection 2016 Nov. HeartRhythm Case Rep. 2016. PMID: 28491751 Free PMC article. No abstract available.
The KCNE Tango - How KCNE1 Interacts with Kv7.1.
Wrobel E, Tapken D, Seebohm G. Wrobel E, et al. Front Pharmacol. 2012 Aug 2;3:142. doi: 10.3389/fphar.2012.00142. eCollection 2012. Front Pharmacol. 2012. PMID: 22876232 Free PMC article.
Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A).
Seebohm G, Wrobel E, Pusch M, Dicks M, Terhag J, Matschke V, Rothenberg I, Ursu ON, Hertel F, Pott L, Lang F, Schulze-Bahr E, Hollmann M, Stoll R, Strutz-Seebohm N. Seebohm G, et al. Among authors: wrobel e. Pflugers Arch. 2014 Oct;466(10):1885-97. doi: 10.1007/s00424-013-1424-8. Epub 2014 Jan 5. Pflugers Arch. 2014. PMID: 24389605 Free PMC article.
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.
Zhang M, D'Aniello C, Verkerk AO, Wrobel E, Frank S, Ward-van Oostwaard D, Piccini I, Freund C, Rao J, Seebohm G, Atsma DE, Schulze-Bahr E, Mummery CL, Greber B, Bellin M. Zhang M, et al. Among authors: wrobel e. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5383-92. doi: 10.1073/pnas.1419553111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453094 Free PMC article.
Klotho: a new trafficking modifier of Kv7.1/KCNE1 channels.
Strutz-Seebohm N, Wrobel E, Schulze-Bahr E, Seebohm G. Strutz-Seebohm N, et al. Among authors: wrobel e. Channels (Austin). 2014;8(4):285. doi: 10.4161/chan.29659. Channels (Austin). 2014. PMID: 25478618 Free PMC article. No abstract available.
The Natural Plant Product Rottlerin Activates Kv7.1/KCNE1 Channels.
Matschke V, Piccini I, Schubert J, Wrobel E, Lang F, Matschke J, Amedonu E, Meuth SG, Strünker T, Strutz-Seebohm N, Greber B, Scherkenbeck J, Seebohm G. Matschke V, et al. Among authors: wrobel e. Cell Physiol Biochem. 2016;40(6):1549-1558. doi: 10.1159/000453205. Epub 2016 Dec 21. Cell Physiol Biochem. 2016. PMID: 27997884 Free article.
In Vitro Analyses of Novel HCN4 Gene Mutations.
Möller M, Silbernagel N, Wrobel E, Stallmayer B, Amedonu E, Rinné S, Peischard S, Meuth SG, Wünsch B, Strutz-Seebohm N, Decher N, Schulze-Bahr E, Seebohm G. Möller M, et al. Among authors: wrobel e. Cell Physiol Biochem. 2018;49(3):1197-1207. doi: 10.1159/000493301. Epub 2018 Sep 7. Cell Physiol Biochem. 2018. PMID: 30196304 Free article.
54 results