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Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.
Bednash JS, Weathington N, Londino J, Rojas M, Gulick DL, Fort R, Han S, McKelvey AC, Chen BB, Mallampalli RK. Bednash JS, et al. Among authors: londino j. Nat Commun. 2017 May 11;8:15203. doi: 10.1038/ncomms15203. Nat Commun. 2017. PMID: 28492230 Free PMC article.
Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation.
Evankovich J, Lear T, Mckelvey A, Dunn S, Londino J, Liu Y, Chen BB, Mallampalli RK. Evankovich J, et al. Among authors: londino j. FASEB J. 2017 Sep;31(9):3894-3903. doi: 10.1096/fj.201700031R. Epub 2017 May 17. FASEB J. 2017. PMID: 28515150 Free PMC article.
These data suggest that modulation of regulators involved in ubiquitin-mediated disposal of RAGE might serve as unique molecular inputs directing RAGE cellular concentrations and downstream responses, which are critical in an array of inflammatory disorders, including acute lung …
These data suggest that modulation of regulators involved in ubiquitin-mediated disposal of RAGE might serve as unique molecular inputs dire …
The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis.
Chandra D, Londino J, Alexander S, Bednash JS, Zhang Y, Friedlander RM, Daskivich G, Carlisle DL, Lariviere WR, Nakassa ACI, Ross M, St Croix C, Nyunoya T, Sciurba F, Chen B, Mallampalli RK. Chandra D, et al. Among authors: londino j. J Mol Cell Cardiol. 2019 Jan;126:50-59. doi: 10.1016/j.yjmcc.2018.11.006. Epub 2018 Nov 16. J Mol Cell Cardiol. 2019. PMID: 30448480 Free PMC article.
KIAA0317 regulates pulmonary inflammation through SOCS2 degradation.
Lear TB, McKelvey AC, Evankovich JW, Rajbhandari S, Coon TA, Dunn SR, Londino JD, McVerry BJ, Zhang Y, Valenzi E, Burton CL, Gordon R, Gingras S, Lockwood KC, Jurczak MJ, Lafyatis R, Shlomchik MJ, Liu Y, Chen BB. Lear TB, et al. Among authors: londino jd. JCI Insight. 2019 Oct 3;4(19):e129110. doi: 10.1172/jci.insight.129110. JCI Insight. 2019. PMID: 31578312 Free PMC article.
34 results