Claiborne AK - Search Results

1

Structure-activity relationships in quinolone antibacterials: design, synthesis and biological activities of novel isothiazoloquinolones.

Chu DT, Fernandes PB, Claiborne AK, Shen L, Pernet AG. Chu DT, et al. Among authors: claiborne ak. Drugs Exp Clin Res. 1988;14(6):379-83. Drugs Exp Clin Res. 1988. PMID: 2850902

2

Synthesis and structure-activity relationships of 2-pyridones: a novel series of potent DNA gyrase inhibitors as antibacterial agents.

Li Q, Chu DT, Claiborne A, Cooper CS, Lee CM, Raye K, Berst KB, Donner P, Wang W, Hasvold L, Fung A, Ma Z, Tufano M, Flamm R, Shen LL, Baranowski J, Nilius A, Alder J, Meulbroek J, Marsh K, Crowell D, Hui Y, Seif L, Melcher LM, Plattner JJ, et al. Li Q, et al. J Med Chem. 1996 Aug 2;39(16):3070-88. doi: 10.1021/jm960207w. J Med Chem. 1996. PMID: 8759628

3

Synthesis and structure-activity relationships of 2-pyridones: II. 8-(Fluoro-substituted pyrrolidinyl)-2-pyridones as antibacterial agents.

Li Q, Wang W, Berst KB, Claiborne A, Hasvold L, Raye K, Tufano M, Nilius A, Shen LL, Flamm R, Alder J, Marsh K, Crowell D, Chu DT, Plattner JJ. Li Q, et al. Bioorg Med Chem Lett. 1998 Aug 4;8(15):1953-8. doi: 10.1016/s0960-894x(98)00355-2. Bioorg Med Chem Lett. 1998. PMID: 9873465

4

Structure-activity relationship of quinolone antibacterial agents: the effects of C-2 substitution.

Chu DT, Lico IM, Claiborne AK, Plattner JJ, Pernet AG. Chu DT, et al. Among authors: claiborne ak. Drugs Exp Clin Res. 1990;16(5):215-24. Drugs Exp Clin Res. 1990. PMID: 1964116

5

Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterial agents.

Chu DT, Fernandes PB, Claiborne AK, Gracey EH, Pernet AG. Chu DT, et al. Among authors: claiborne ak. J Med Chem. 1986 Nov;29(11):2363-9. doi: 10.1021/jm00161a036. J Med Chem. 1986. PMID: 3783594

6

Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents.

Chu DT, Fernandes PB, Claiborne AK, Pihuleac E, Nordeen CW, Maleczka RE Jr, Pernet AG. Chu DT, et al. Among authors: claiborne ak. J Med Chem. 1985 Nov;28(11):1558-64. doi: 10.1021/jm00149a003. J Med Chem. 1985. PMID: 3934382

7

Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors.

Li Q, Claiborne A, Li T, Hasvold L, Stoll VS, Muchmore S, Jakob CG, Gu W, Cohen J, Hutchins C, Frost D, Rosenberg SH, Sham HL. Li Q, et al. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5367-70. doi: 10.1016/j.bmcl.2004.08.012. Bioorg Med Chem Lett. 2004. PMID: 15454228

8

Synthesis and activity of 1-aryl-1'-imidazolyl methyl ethers as non-thiol farnesyltransferase inhibitors.

Li Q, Wang GT, Li T, Gwaltney SL 2nd, Woods KW, Claiborne A, Wang X, Gu W, Cohen J, Stoll VS, Hutchins C, Frost D, Rosenberg SH, Sham HL. Li Q, et al. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5371-6. doi: 10.1016/j.bmcl.2004.08.011. Bioorg Med Chem Lett. 2004. PMID: 15454229

9

Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors.

Li Q, Woods KW, Wang W, Lin NH, Claiborne A, Gu WZ, Cohen J, Stoll VS, Hutchins C, Frost D, Rosenberg SH, Sham HL. Li Q, et al. Bioorg Med Chem Lett. 2005 Apr 15;15(8):2033-9. doi: 10.1016/j.bmcl.2005.02.062. Bioorg Med Chem Lett. 2005. PMID: 15808463

10

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors.

Woods KW, Fischer JP, Claiborne A, Li T, Thomas SA, Zhu GD, Diebold RB, Liu X, Shi Y, Klinghofer V, Han EK, Guan R, Magnone SR, Johnson EF, Bouska JJ, Olson AM, de Jong R, Oltersdorf T, Luo Y, Rosenberg SH, Giranda VL, Li Q. Woods KW, et al. Bioorg Med Chem. 2006 Oct 15;14(20):6832-46. doi: 10.1016/j.bmc.2006.06.047. Epub 2006 Jul 14. Bioorg Med Chem. 2006. PMID: 16843670

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